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Published in 2022 at "BMJ Open"
DOI: 10.1136/bmjopen-2022-063436
Abstract: Objective A deep understanding of the relationship between a scarce drug's dose and clinical response is necessary to appropriately distribute a supply-constrained drug along these lines. Summary of key data The vast majority of drug…
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Keywords:
optimisation;
dose optimisation;
scarce resource;
resource allocation ... See more keywords
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1
Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.833303
Abstract: Experience in the clinical use of posaconazole (PCZ) in pediatric patients is limited, and no specific dose recommendations exist. This study aimed to investigate an appropriate dosing regimen, and assess the exposure-response relationships of PCZ…
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Keywords:
dose optimisation;
pcz;
pcz concentrations;
optimisation posaconazole ... See more keywords