Efficacy and Safety of Pyronaridine-Artesunate plus Single-Dose Primaquine for the Treatment of Malaria in Western Cambodia
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DOI: 10.1128/aac.01273-19
Abstract: This single-arm trial (n = 104) in western Cambodia showed high efficacy for 3-day treatment with pyronaridine-artesunate plus single-dose primaquine in Plasmodium falciparum malaria. ABSTRACT This single-arm trial (n = 104) in western Cambodia showed high efficacy for 3-day… read more here.
Keywords: western cambodia; pyronaridine artesunate; single dose; plus single ... See more keywords
Modelling the therapeutic dose range of single low dose primaquine to reduce malaria transmission through age-based dosing
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DOI: 10.1186/s12879-017-2378-9
Abstract: BackgroundLow-dose primaquine is a key candidate for use in malaria transmission reduction and elimination campaigns such as mass drug administration (MDA). Uncertainty about the therapeutic dose range (TDR) required for general and paediatric populations challenge… read more here.
Keywords: dose range; age; age based; dose primaquine ... See more keywords
Single dose primaquine to reduce gametocyte carriage and Plasmodium falciparum transmission in Cambodia: An open-label randomized trial
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DOI: 10.1371/journal.pone.0168702
Abstract: Background Single low dose primaquine (SLD PQ, 0.25mg/kg) is recommended in combination with artemisinin-based combination therapy (ACT) as a gametocytocide to prevent Plasmodium falciparum transmission in areas threatened by artemisinin resistance. To date, no randomized… read more here.
Keywords: dhp; transmission; falciparum; dose primaquine ... See more keywords