Busulfan Interlaboratory Proficiency Testing Program Revealed Worldwide Errors in Drug Quantitation and Dose Recommendations.
Sign Up to like & getrecommendations! Published in 2023 at "Therapeutic drug monitoring"
DOI: 10.1097/ftd.0000000000001107
Abstract: BACKGROUND The clinical outcomes of busulfan-based conditioning regimens for hematopoietic cell transplantation (HCT) have been improved by personalizing the doses to target narrow busulfan plasma exposure. An interlaboratory proficiency test program for the quantitation, pharmacokinetic… read more here.
Keywords: proficiency; proficiency test; dose recommendations; busulfan ... See more keywords
Lithium replacement dose recommendations using Monte Carlo simulations
Sign Up to like & getrecommendations! Published in 2022 at "Bipolar Disorders"
DOI: 10.1111/bdi.13241
Abstract: Missed medication doses are a common clinical problem, and cause consternation when prescribing lithium because its plasma levels must be kept within a narrow therapeutic window. Therefore, this study set out to determine the potential… read more here.
Keywords: monte carlo; lithium replacement; replacement dose; dose recommendations ... See more keywords
CYP2D6 Genotype-Based Dose Recommendations for Risperidone in Asian People
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.00936
Abstract: The aim of this study was to provide dose recommendations for risperidone in Asian people based on cytochrome P450 enzyme CYP2D6 genotype. First, we investigated the influence of CYP2D6 polymorphism on the pharmacokinetics of risperidone… read more here.
Keywords: dose recommendations; recommendations risperidone; risperidone asian; cyp2d6 genotype ... See more keywords