Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants: A Review.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2022.1292
Abstract: Importance Dose-reduced regimens of direct oral anticoagulants (DOACs) may be used for 2 main purposes: dose-adjusted treatment intended as full-intensity anticoagulation (eg, for stroke prevention in atrial fibrillation [AF] in patients requiring dose reduction) or… read more here.
Keywords: dose adjusted; low intensity; treatment; dose reduced ... See more keywords
Anti-TNF dose can be reduced in PsA and axSpA
Sign Up to like & getrecommendations! Published in 2021 at "Nature Reviews Rheumatology"
DOI: 10.1038/s41584-021-00714-y
Abstract: Results from a retrospective cohort study suggest that use of a disease activityguided dose optimization (DAGDO) strategy to taper TNF inhibitor therapy is safe and effective in patients with psoriatic arthritis (PsA) or axial spondyloarthritis… read more here.
Keywords: tnf; dose reduced; period; anti tnf ... See more keywords
Evaluating the Response of Palbociclib on Progression Free Survival in Hormone Receptor Positive Metastatic Breast Cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Oncology"
DOI: 10.1159/000524340
Abstract: BACKGROUND In patients with hormone receptor positive metastatic breast cancer, Palbociclib has been shown to improve overall survival and progression-free survival (PFS) when combined with endocrine therapy. Dose modification of palbociclib is effective in the… read more here.
Keywords: palbociclib; breast cancer; dose reduced; metastatic breast ... See more keywords