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   Articles with "dose reduced" as a keyword



Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants: A Review.

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recommendations! Published in 2022 at "JAMA cardiology"

DOI: 10.1001/jamacardio.2022.1292

Abstract: Importance Dose-reduced regimens of direct oral anticoagulants (DOACs) may be used for 2 main purposes: dose-adjusted treatment intended as full-intensity anticoagulation (eg, for stroke prevention in atrial fibrillation [AF] in patients requiring dose reduction) or… read more here.

Keywords: dose adjusted; low intensity; treatment; dose reduced ... See more keywords

Anti-TNF dose can be reduced in PsA and axSpA

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recommendations! Published in 2021 at "Nature Reviews Rheumatology"

DOI: 10.1038/s41584-021-00714-y

Abstract: Results from a retrospective cohort study suggest that use of a disease activityguided dose optimization (DAGDO) strategy to taper TNF inhibitor therapy is safe and effective in patients with psoriatic arthritis (PsA) or axial spondyloarthritis… read more here.

Keywords: tnf; dose reduced; period; anti tnf ... See more keywords

Evaluating the Response of Palbociclib on Progression Free Survival in Hormone Receptor Positive Metastatic Breast Cancer.

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recommendations! Published in 2022 at "Oncology"

DOI: 10.1159/000524340

Abstract: BACKGROUND In patients with hormone receptor positive metastatic breast cancer, Palbociclib has been shown to improve overall survival and progression-free survival (PFS) when combined with endocrine therapy. Dose modification of palbociclib is effective in the… read more here.

Keywords: palbociclib; breast cancer; dose reduced; metastatic breast ... See more keywords

Assessing treatment outcomes of enfortumab vedotin dose reduction in metastatic bladder cancer.

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recommendations! Published in 2025 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2025.43.16_suppl.4576

Abstract: 4576 Background: Enfortumab Vedotin (EV), an antibody drug conjugate targeting Nectin-4, has emerged as first-line treatment for advanced Urothelial Carcinoma (UC) in combination with pembrolizumab. Acute and cumulative toxicity due to EV can adversely impact… read more here.

Keywords: enfortumab vedotin; dose reduction; treatment; dose reduced ... See more keywords
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Dose-Reduced FLA-IDA in Combination with Venetoclax Is an Effective and Safe Salvage Therapy in Relapsed and Refractory Acute Myeloid Leukemia (R/R AML)

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recommendations! Published in 2024 at "Cancers"

DOI: 10.3390/cancers16223872

Abstract: Simple Summary In this single-center study, we aimed to assess safety and efficacy in patients undergoing a dose-reduced, 4-day salvage regimen of FLA-VIDA in comparison to full-dose FLA-VIDA, and FLA-IDA alone, to reduce the duration… read more here.

Keywords: fla ida; reduced fla; dose reduced; salvage ... See more keywords