Pre‐clinical in vitro infection models
Sign Up to like & getrecommendations! Published in 2017 at "Current Opinion in Pharmacology"
DOI: 10.1016/j.coph.2017.09.011
Abstract: HIGHLIGHTSIn vitro systems allow determination of dose and schedule for new drugs.Identifying this allows better patient outcomes and de‐risks drug development.The HFIM allows identification of dose and schedule for resistance suppression. &NA; Given the current… read more here.
Keywords: dose schedule; clinical vitro; pre clinical; vitro infection ... See more keywords
34. Impact of Universal Mass Vaccination Programs of Children Against Hepatitis a with 2-dose and 1-dose Schedules: A Systematic Literature Review
Sign Up to like & getrecommendations! Published in 2020 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofaa417.033
Abstract: Abstract Background With more than 100 million new hepatitis A (HepA) virus (HAV) infections estimated each year, HepA is a serious health concern worldwide. Several countries implemented 2- or 1-dose universal mass vaccination (UMV) programs… read more here.
Keywords: dose schedule; umv programs; gsk group; vaccination ... See more keywords
Modeling Dose and Schedule Effects of AZD2811 Nanoparticles Targeting Aurora B Kinase for Treatment of Diffuse Large B-cell Lymphoma
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Cancer Therapeutics"
DOI: 10.1158/1535-7163.mct-18-0577
Abstract: Barasertib (AZD1152), a pro-drug of the highly potent and selective Aurora B kinase inhibitor AZD2811, showed promising clinical activity in relapsed/refractory diffuse large B-cell lymphoma (DLBCL) patients administered as a 4-day infusion. To improve potential… read more here.
Keywords: aurora kinase; dose schedule; tumor; cell ... See more keywords
Human papillomavirus vaccination update: Nonavalent vaccine and the two-dose schedule.
Sign Up to like & getrecommendations! Published in 2018 at "Australian journal of general practice"
DOI: 10.31128/ajgp-01-18-4462
Abstract: BACKGROUND Australia has included quadrivalent human papillomavirus (HPV) vaccination in its national program since 2007. Significant declines have been observed in the incidence of HPV infection, genital warts and high-grade cervical lesions. In 2018, the… read more here.
Keywords: dose schedule; two dose; hpv; vaccine ... See more keywords