Clinical Study of Standard- vs Reduced-Dose Tacrolimus Combined With Generic Mycophenolate Mofetil in De Novo Kidney Transplantation: A Prospective Randomized Trial.
Sign Up to like & getrecommendations! Published in 2019 at "Transplantation proceedings"
DOI: 10.1016/j.transproceed.2019.11.029
Abstract: BACKGROUND The lowering of calcineurin inhibitor exposure is possibly considered as the proper strategy to prevent calcineurin inhibitor-induced nephrotoxicity in kidney transplant. This clinical study was designed to compare the efficacy and tolerability of reduced-dose… read more here.
Keywords: reduced dose; dose tacrolimus; group; standard dose ... See more keywords
Immunosuppressive effect of the gut microbiome altered by high‐dose tacrolimus in mice
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DOI: 10.1111/ajt.14661
Abstract: The alterations induced in gut microbiota by tacrolimus may affect immune function and organ transplantation. Mice were treated with high‐dose tacrolimus for 14 days. The fecal microbiota were analyzed by pyrosequencing the 16S rRNA genes,… read more here.
Keywords: dose tacrolimus; tacrolimus; high dose; gut microbiome ... See more keywords
Viral‐specific cytotoxic T‐cell responses in HLA‐sensitized kidney transplant patients maintained on everolimus and low‐dose tacrolimus
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DOI: 10.1111/tid.13805
Abstract: Maintenance with “everolimus + reduced dose tacrolimus” (Ev + Taclow) was reported to reduce the risk of viral infections compared to “tacrolimus + mycophenolate mofetil” (Tac + MMF). Here we examined viremia and viral‐specific T‐cell… read more here.
Keywords: dose tacrolimus; hla sensitized; specific cytotoxic; viral specific ... See more keywords