Dose‐ and time‐dependent alterations in lipid metabolism after pharmacological PGC‐1α activation in L6 myotubes
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27872
Abstract: Pyrroloquinoline quinone (PQQ) acts as a powerful modulator of PGC‐1α activation and therefore regulates multiple pathways involved in cellular energy homeostasis. In the present study, we assessed the effects of L6 myotubes incubation with 0.5,… read more here.
Keywords: time dependent; dose time; pgc; pgc activation ... See more keywords
Exposure to intranasal chromium triggers dose and time-dependent behavioral and neurotoxicological defects in rats.
Sign Up to like & getrecommendations! Published in 2021 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2021.112220
Abstract: The extensive recorded environmental and occupational dispersal of hexavalent chromium (CrVI) dust contributes to an increased interest in its toxicological consequences. A previous study of our team described a brain injury induced by acute intranasal… read more here.
Keywords: exposure intranasal; time dependent; dose time; brain ... See more keywords
Dose and Time Response Study to Develop Retinal Degenerative Model of Zebrafish with Lead Acetate.
Sign Up to like & getrecommendations! Published in 2021 at "Cutaneous and ocular toxicology"
DOI: 10.1080/15569527.2021.1999254
Abstract: Animal models are the silent scouts that help to understand the complex biological processes and gather data that aid our understanding of how organisms function. Various animal models are being sacrificed to assess the impact… read more here.
Keywords: response study; response; study; dose time ... See more keywords
Response to: ‘Dose–time–response association between occupational asbestos exposure and pleural mesothelioma’ by Lacourt et al
Sign Up to like & getrecommendations! Published in 2017 at "Occupational and Environmental Medicine"
DOI: 10.1136/oemed-2017-104570
Abstract: The study by Lacourt reported in a recent issue of Occup Environ Med 1 does not satisfy two fundamental requirements of the design and conduct of a case–control study: these limitations invalidate its results and… read more here.
Keywords: response; mesothelioma; response dose; dose time ... See more keywords
DynOVis: a web tool to study dynamic perturbations for capturing dose-over-time effects in biological networks
Sign Up to like & getrecommendations! Published in 2019 at "BMC Bioinformatics"
DOI: 10.1186/s12859-019-2995-y
Abstract: BackgroundThe development of high throughput sequencing techniques provides us with the possibilities to obtain large data sets, which capture the effect of dynamic perturbations on cellular processes. However, because of the dynamic nature of these… read more here.
Keywords: network; biological networks; dose time; gene ... See more keywords
The Dose- and Time-Dependent Cytotoxic Effect of Graphene Nanoplatelets: In Vitro and In Vivo Study
Sign Up to like & getrecommendations! Published in 2022 at "Nanomaterials"
DOI: 10.3390/nano12121978
Abstract: Graphene-based nanomaterials received attention from scientists due to their unique properties: they are highly conductive, mechanically resistant and elastic. These materials can be used in different sectors of society from electronic energy storage in industry… read more here.
Keywords: graphene; time; vitro vivo; dose time ... See more keywords