Are the loading dose treatment groups superior to the 150 mg without loading dose group in the secukinumab FUTURE 5 study
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-213770
Abstract: I read with great interest the article by Mease et al 1 because equivalence in efficacy with lesser secukinumab total doses could be less expensive to payers and more safe and comfortable to patients. However, I am… read more here.
Keywords: loading dose; 150 without; treatment groups; superior 150 ... See more keywords
Effect of escitalopram dose and treatment duration on CSF Aβ levels in healthy older adults
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DOI: 10.1212/wnl.0000000000010725
Abstract: Objective To determine whether treatment with escitalopram compared with placebo would lower CSF β-amyloid 42 (Aβ42) levels. Rationale Serotonin signaling suppresses Aβ42 in animal models of Alzheimer disease (AD) and young healthy humans. In a… read more here.
Keywords: treatment duration; csf levels; older adults; csf ... See more keywords