High Doses of Drugs Extensively Metabolized by CYP3A4 Were Needed to Reach Therapeutic Concentrations in Two Patients Taking Inducers.
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DOI: 10.1016/j.rcp.2018.07.002
Abstract: INTRODUCTION In the last 20 years of clinical practice, the senior author has identified these 2 rare cases in which the patients needed extremely high doses of drugs metabolized by CYP3A4 to reach and maintain… read more here.
Keywords: doses drugs; high doses; therapeutic concentrations; day ... See more keywords