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Single low doses of MPTP decrease tyrosine hydroxylase expression in the absence of overt neuron loss

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Published in 2017 at "Neurotoxicology"

DOI: 10.1016/j.neuro.2017.03.008

Abstract: HIGHLIGHTSLow doses of MPTP cause loss of TH expression rather than actual loss of neurons.Higher doses of MPTP cause both loss of TH expression and neurons.Striatal dopamine levels and terminal marker loss are consistent with… read more here.

Keywords: loss; dopamine; doses mptp; expression ... See more keywords