A phase I study of the effect of repeated oral doses of pantoprazole on the pharmacokinetics of a single dose of fedratinib in healthy male subjects
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DOI: 10.1007/s00280-020-04074-4
Abstract: Purpose Fedratinib, an oral, selective Janus kinase 2 inhibitor with activity against both wild-type and mutant Janus kinase 2, has pH-dependent solubility, with free solubility at pH 1. Concomitant administration of drugs that reduce gastric… read more here.
Keywords: healthy male; study; male subjects; doses pantoprazole ... See more keywords