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Published in 2023 at "Journal of clinical pharmacology"
DOI: 10.1002/jcph.2283
Abstract: Direct oral anticoagulants (DOACs) are indicated for the prevention of stroke in non-valvular atrial fibrillation (NVAF). Although FDA labeling for DOACs utilizes estimated creatinine clearance (CrCL) according to the Cockcroft-Gault (C-G) equation, estimated glomerular filtration…
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Keywords:
estimates kidney;
kidney function;
doac dosing;
dosing discordance ... See more keywords
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Published in 2020 at "Annals of Pharmacotherapy"
DOI: 10.1177/1060028020922492
Abstract: Background: Numerous equations exist for estimating renal clearance for drug dosing, and discordance rates may be as high as 40% in certain populations. However, the populations and types of equations used in these studies may…
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Keywords:
discordance;
renal estimating;
ckd epi;
dosing discordance ... See more keywords