Articles with "dosing neonates" as a keyword



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Individualized Empiric Vancomycin Dosing in Neonates Using a Model-Based Approach.

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Published in 2019 at "Journal of the Pediatric Infectious Diseases Society"

DOI: 10.1093/jpids/pix109

Abstract: BACKGROUND Vancomycin dosing in neonates is challenging because of the large variation in pharmacokinetics. Existing empiric dosing recommendations use table-based formats, within which a neonate is categorized on the basis of underlying characteristics. The ability… read more here.

Keywords: model based; vancomycin dosing; neo vanco; dosing neonates ... See more keywords
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Maturational changes in vancomycin protein binding affect vancomycin dosing in neonates

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Published in 2019 at "British Journal of Clinical Pharmacology"

DOI: 10.1111/bcp.13899

Abstract: Optimal dosing of vancomycin in neonates remains a matter of debate despite the frequent use of vancomycin in neonatal intensive care units (NICUs). The optimal use of vancomycin requires knowledge of its pharmacokinetics (PK) and… read more here.

Keywords: vancomycin; auc24 mic; maturational changes; dosing neonates ... See more keywords