Matching-adjusted indirect comparison of talquetamab vs selinexor-dexamethasone and vs belantamab mafodotin in patients with relapsed/refractory multiple myeloma
Sign Up to like & getrecommendations! Published in 2024 at "Current Medical Research and Opinion"
DOI: 10.1080/03007995.2024.2391553
Abstract: Abstract Objective Talquetamab is the first GPRC5D-targeting bispecific antibody approved for the treatment of triple-class exposed (TCE) relapsed/refractory multiple myeloma (RRMM). This matching-adjusted indirect comparison (MAIC) study was conducted to compare the effectiveness of talquetamab… read more here.
Keywords: dosing schedules; talquetamab; sel dex; refractory multiple ... See more keywords
P0341RITUXIMAB IN THE TREATMENT OF PRIMARY MEMBRANOUS NEPHROPATHY - A COMPARATIVE STUDY OF THREE REGIMEN
Sign Up to like & getrecommendations! Published in 2020 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfaa144.p0341
Abstract: Different rituximab dosing schedules have been used to manage primary membranous nephropathy (PMN). Better response rate and toxicity needs to be balanced to arrive at correct dose. The dosing schedules in PMN as of now… read more here.
Keywords: dosing schedules; treatment; remission; study ... See more keywords
Impact of dosing schedules on performance of rotavirus vaccines in Ghana
Sign Up to like & getrecommendations! Published in 2024 at "Science Advances"
DOI: 10.1126/sciadv.adn4176
Abstract: There is currently limited evidence regarding how the rotavirus vaccine dosing schedule might be adjusted to improve vaccine performance. We quantified the impact of the previously implemented 6/10-week Rotarix vaccine (RV1) in Ghana to the… read more here.
Keywords: dosing schedules; reductions rotavirus; performance; vaccine ... See more keywords
Abstract 5582: Use of circulating tumor DNA (ctDNA) to predict superiority of dosing schedules in early clinical development
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-5582
Abstract: Changes in ctDNA can be used as a surrogate molecular marker of response to determine clinical efficacy and often precede imaging changes. This analysis is valuable to early clinical trials for dose optimization as response… read more here.
Keywords: early clinical; ctdna; dosing schedules; circulating tumor ... See more keywords
A modeling-based approach to optimize COVID-19 vaccine dosing schedules for improved protection.
Sign Up to like & getrecommendations! Published in 2023 at "JCI insight"
DOI: 10.1172/jci.insight.169860
Abstract: While the development of different vaccines slowed the dissemination of SARS-CoV-2, the occurrence of breakthrough infections has continued to fuel the COVID-19 pandemic. To at least secure partial protection in majority of the population through… read more here.
Keywords: breakthrough infections; protection; vaccine dosing; covid vaccine ... See more keywords
Escalated dosing schedules of CC-486 for patients experiencing first acute myeloid leukemia (AML) relapse: Results from the phase III QUAZAR AML-001 maintenance trial.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.7513
Abstract: 7513Background: A goal of AML maintenance therapy is to decrease the risk of relapse by suppressing growth of residual leukemic cells post-induction. CC-486 is an oral hypomethylating agent that al... read more here.
Keywords: schedules 486; dosing schedules; maintenance; relapse ... See more keywords