Comparison of different dosing strategies of intratracheally instilled budesonide on meconium injured piglet lungs
Sign Up to like & getrecommendations! Published in 2017 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.23697
Abstract: Severe inflammation plays a vital role in the pathogenesis of meconium aspiration syndrome (MAS). Intratracheal (IT) instillation of corticosteroids may be beneficial for MAS in optimizing local effect and reducing systemic adverse effects, but the… read more here.
Keywords: intratracheally instilled; dosing strategies; meconium; different dosing ... See more keywords
COMPARISON OF ALTEPLASE DOSING STRATEGIES IN PATIENTS UNDERGOING CATHETER DIRECTED THROMBOLYSIS FOR ACUTE PULMONARY EMBOLISM
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American College of Cardiology"
DOI: 10.1016/s0735-1097(20)32028-3
Abstract: Catheter directed thrombolysis (CDT) has become a recommended treatment in high risk pulmonary embolism (PE). Optimal dosing is unknown. We aimed to evaluate the effect of different dosing strategies on fibrinogen concentrations, bleeding events, and… read more here.
Keywords: catheter directed; directed thrombolysis; pulmonary embolism; dosing strategies ... See more keywords
Comparing clinical outcomes between two scorpion antivenom dosing strategies in children
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Toxicology"
DOI: 10.1080/15563650.2018.1551546
Abstract: Abstract Background and Objectives: The clinical course from scorpion envenomation can range from mild to life threatening, particularly in younger children. The F(ab’)2 antivenom currently available in the United States is extremely effective for countering… read more here.
Keywords: single vial; dosing strategies; clinical outcomes; group ... See more keywords
#329 Effectiveness of dosing strategies of polymyxin B among sepsis patients with and without renal replacement therapies
Sign Up to like & getrecommendations! Published in 2024 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfae069.827
Abstract: Despite numerous population pharmacokinetic studies on polymyxin B, a gap exists in establishing uniform dosing strategies among sepsis patients due to various clinical and patient related factors. The International Consensus guidelines, provide detailed dosing calculation… read more here.
Keywords: polymyxin; sepsis patients; dose 150; among sepsis ... See more keywords
OPTIMAL DOSING STRATEGIES AGAINST SUSCEPTIBLE AND RESISTANT BACTERIA
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biological Systems"
DOI: 10.1142/s0218339018500031
Abstract: Mathematical models can be very useful in determining efficient and successful antibiotic dosing techniques against bacterial infections. There are several challenging issues involved, the presence of drug resistant bacteria being one. Recent rise in antibiotic… read more here.
Keywords: optimal dosing; susceptible resistant; dosing strategies; resistant bacteria ... See more keywords
4-Factor Prothrombin Complex Concentrate Dosing Strategies: A Retrospective Evaluation.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of pharmacy practice"
DOI: 10.1177/08971900221131924
Abstract: ObjectivesDetermine indication specific 4-Factor prothrombin complex concentrate (4FPCC) dosing strategies within a hospital system and subsequent effectiveness. Background: 4FPCC is FDA approved for reversal of vitamin K antagonists (VKA) for acute major bleeding or need… read more here.
Keywords: factor prothrombin; complex concentrate; dosing; dosing strategies ... See more keywords
Different dosing strategies of pembrolizumab in the treatment of NSCLC: A real-world retrospective observational study.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2024.42.16_suppl.e23264
Abstract: e23264 Background: Immune checkpoint inhibitors lack a dose-response relationship, allowing optimisation of dosing strategies that may reduce drug use. Pembrolizumab received its initial regulatory approval for the treatment of non-small cell lung cancer (NSCLC) at… read more here.
Keywords: treatment; pembrolizumab; use; flat dosing ... See more keywords
Methylene blue dosing strategies in critically ill adults with shock—A retrospective cohort study
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.1014276
Abstract: Background Shock increases mortality in the critically ill and the mainstay of therapy is the administration of vasopressor agents to achieve hemodynamic targets. In the past, studies have found that the NO-pathway antagonist methylene blue… read more here.
Keywords: methylene; methylene blue; dosing strategies; mortality ... See more keywords
Assessing chemotherapy dosing strategies in a spatial cell culture model
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.980770
Abstract: Predicting patient responses to chemotherapy regimens is a major challenge in cancer treatment. Experimental model systems coupled with quantitative mathematical models to calculate optimal dose and frequency of drugs can enable improved chemotherapy regimens. Here… read more here.
Keywords: cell; chemotherapy dosing; dosing strategies; model ... See more keywords
Tigecycline Dosing Strategies in Critically Ill Liver-Impaired Patients
Sign Up to like & getrecommendations! Published in 2022 at "Antibiotics"
DOI: 10.3390/antibiotics11040479
Abstract: This study investigated tigecycline exposure in critically ill patients from a population pharmacokinetic perspective to support rational dosing in intensive care unit (ICU) patients with acute and chronic liver impairment. A clinical dataset of 39… read more here.
Keywords: critically ill; pugh score; tigecycline dosing; dosing strategies ... See more keywords