Articles with "dot1l function" as a keyword



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The Role of DOT1L in Normal and Malignant Hematopoiesis

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Published in 2022 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2022.917125

Abstract: Disruptor of telomeric silencing 1 (DOT1) was first identified in yeast (DOT1p) and is the sole methyltransferase responsible for histone three lysine 79 (H3K79) mono-, di-, and tri-methylation. Mammalian DOT1 (DOT1-like protein or DOT1L) has… read more here.

Keywords: dot1l function; dot1l normal; dot1l; hematopoiesis ... See more keywords