Articles with "dot1l mediated" as a keyword



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DOT1L Mediated Gene Repression in Extensively Self-Renewing Erythroblasts

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Published in 2022 at "Frontiers in Genetics"

DOI: 10.3389/fgene.2022.828086

Abstract: DOT1L is essential for embryonic hematopoiesis but the precise mechanisms of its action remain unclear. The only recognized function of DOT1L is histone H3 lysine 79 (H3K79) methylation, which has been implicated in both transcriptional… read more here.

Keywords: dot1l mediated; self renewing; dot1l; extensively self ... See more keywords