Primitive Erythropoiesis in the Mouse is Independent of DOT1L Methyltransferase Activity
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DOI: 10.3389/fcell.2021.813503
Abstract: DOT1-like (DOT1L) histone methyltransferase is essential for mammalian erythropoiesis. Loss of DOT1L in knockout (Dot1l-KO) mouse embryos resulted in lethal anemia at midgestational age. The only recognized molecular function of DOT1L is its methylation of… read more here.
Keywords: dot1l methyltransferase; dot1l; methyltransferase; methyltransferase activity ... See more keywords