[68Ga]Ga-DOTA-FAPI-04 improves tumor staging and monitors early response to chemoradiotherapy in a patient with esophageal cancer
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-020-04818-7
Abstract: The main limitation of [F]FDG PET/CT in staging of esophageal cancer is its low-to-moderate sensitivity for lymph node staging [1, 2]. Previous studies demonstrated that [Ga]GaDOTA-FAPI-04 PET/CT allowed imaging of esophageal cancer with high tumor-to-background… read more here.
Keywords: esophageal cancer; tumor staging; dota fapi; fapi ... See more keywords
Reply: [68Ga]Ga-DOTA-FAPI-04 and [18F]FDG PET/CT for the diagnosis of primary and metastatic lesions in patients with hepatic cancer
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-020-04866-z
Abstract: Dear Sir, We would like to thank Dr. Yao and his colleagues for the important insights into the article “Comparison of [Ga]GaDOTA-FAPI-04 and [F]FDG PET/CT for the diagnosis of primary and metastatic lesions in patients… read more here.
Keywords: diagnosis; mass; fdg pet; dota fapi ... See more keywords
A theranostic approach of [68Ga]Ga-DOTA.SA.FAPi PET/CT-guided [177Lu]Lu-DOTA.SA.FAPi radionuclide therapy in an end-stage breast cancer patient: new frontier in targeted radionuclide therapy
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-020-04990-w
Abstract: A 31-year-young female was diagnosed with breast cancer in September 2019. The histopathology revealed atypical cells arranged cords and tubules in the fibrotic stroma suggestive of invasive ductal carcinoma of the breast and the immunohistochemistry… read more here.
Keywords: pet; dota fapi; fig; radionuclide therapy ... See more keywords
Biodistribution, pharmacokinetics, dosimetry of [68Ga]Ga-DOTA.SA.FAPi, and the head-to-head comparison with [18F]F-FDG PET/CT in patients with various cancers
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-020-05132-y
Abstract: [68Ga]Ga-labeled fibroblast activation protein inhibitors ([68Ga]Ga-FAPi) have shown promising preclinical and clinical results in PET imaging. The present study aimed to evaluate the biodistribution, pharmacokinetics, and dosimetry of [68Ga]Ga-DOTA.SA.FAPi, another modified FAPi tracer, and performed… read more here.
Keywords: various cancers; 68ga dota; dota fapi; 18f fdg ... See more keywords
Development of Fibroblast Activation Protein Inhibitor-Based Dimeric Radiotracers with Improved Tumor Retention and Antitumor Efficacy.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c00424
Abstract: Fibroblast activation protein (FAP), a fundamental component of the tumor stroma, is overexpressed in cancer-associated fibroblasts (CAFs). As a promising theranostic probe, we evaluated whether the FAP inhibitor (FAPI) dimer (DOTA-2P[FAPI]2) is more effective than… read more here.
Keywords: fapi; dota fapi; retention; 177lu dota ... See more keywords
The 68Ga-DOTA-FAPI-04 PET/CT for the differential diagnosis of solitary fibroma of pleura from other chest disease with low uptake of 18F-FDG
Sign Up to like & getrecommendations! Published in 2022 at "Nuclear Medicine Communications"
DOI: 10.1097/mnm.0000000000001579
Abstract: Objective We conducted a prospective study using 68Ga-DOTA-FAPI-04 PET/computed tomography (CT) to differentiate solitary fibromas of pleura (SFP) from other chest similar masses showing low uptake of 18F-FDG. Methods A prospective study including 13 patients… read more here.
Keywords: uptake 18f; 18f fdg; dota fapi; 68ga dota ... See more keywords
Solitary Fibrous Tumors of the Pleura Shown on 18F-FDG and 68Ga-DOTA-FAPI-04 PET/CT.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical nuclear medicine"
DOI: 10.1097/rlu.0000000000003598
Abstract: ABSTRACT A 52-year-old man complained of pain in the right lower chest wall for a month. Chest CT found a subpleural mass, but failed to identify the nature of the tumor. The 18F-FDG PET/CT was… read more here.
Keywords: solitary fibrous; fibrous tumors; dota fapi; 18f fdg ... See more keywords
68Ga-DOTA-FAPI-04 Uptake of Accessory Breast in a Patient With Breast Cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical nuclear medicine"
DOI: 10.1097/rlu.0000000000004069
Abstract: ABSTRACT 68Ga-DOTA-FAPI-04 is a promising PET agent for tumor imaging. However, some nonneoplastic lesions can also show increased FAPI uptake. Herein, we presented a case of a patient with left breast cancer who showed a… read more here.
Keywords: dota fapi; breast; accessory breast; fapi uptake ... See more keywords
Tumor Imaging With 68Ga-DOTA-FAPI-04 PET/CT
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Nuclear Medicine"
DOI: 10.1097/rlu.0000000000004073
Abstract: Introduction and Aim Cancer-associated fibroblasts, which are densely found in tumor tissue, express high levels of fibroblast activation protein (FAP), and FAP inhibitors (FAPIs) labeled with radionuclides can be used in the diagnosis and treatment… read more here.
Keywords: fapi pet; dota fapi; 18f fdg; 68ga dota ... See more keywords
68Ga-DOTA-FAPI-04 PET/CT Imaging in a Case of Cardiac Angiosarcoma.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical nuclear medicine"
DOI: 10.1097/rlu.0000000000004211
Abstract: ABSTRACT A 30-year-old woman presented with sudden syncope. Further examination revealed a mass in the right atrium. 18F-FDG showed increased tracer uptake in the mass. 68Ga-DOTA-FAPI-04 showed increased tracer uptake of thickened pericardium around the… read more here.
Keywords: dota fapi; 68ga dota; mass; angiosarcoma ... See more keywords
The Manifestation of a Patient With Myelofibrosis in 68Ga-DOTA-FAPI-04 PET/CT Mimicking "Super Bone Imaging".
Sign Up to like & getrecommendations! Published in 2022 at "Clinical nuclear medicine"
DOI: 10.1097/rlu.0000000000004427
Abstract: ABSTRACT Primary myelofibrosis is a chronic inflammatory disease of the bone marrow. It progresses from an early robust inflammatory state to a more advanced fibrotic response, representing the advanced stage of the disease. We report… read more here.
Keywords: dota fapi; bone; pet; 68ga dota ... See more keywords