Improvement of DNA Vector Delivery of DOTAP Lipoplexes by Short-Chain Aminolipids
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DOI: 10.1021/acsomega.0c03303
Abstract: Cellular delivery of DNA vectors for the expression of therapeutic proteins is a promising approach to treat monogenic disorders or cancer. Significant efforts in a preclinical and clinical setting have been made to develop potent… read more here.
Keywords: dotap; dna; delivery; dna vector ... See more keywords
Evaluation of Immune Response against Leishmaniasis in BALB/c Mice Immunized with Cationic DOTAP/DOPE/CHOL Liposomes Containing Soluble Leishmania major Antigens
Sign Up to like & getrecommendations! Published in 2019 at "Iranian Journal of Parasitology"
DOI: 10.18502/ijpa.v14i1.719
Abstract: Background: Whole killed Leishmania vaccine reached phase III clinical trials but failed to display significant efficacy in human mainly due to limited Th1 inducer adjuvant. Liposomes consisting of 1, 2-dioleoyl-3trimethylammonium-propane (DOTAP) bearing an inherent adjuvanticity… read more here.
Keywords: mice; response; dotap; sla ... See more keywords