T cell‐dependent antigen adjuvanted with DOTAP‐CpG‐B but not DOTAP‐CpG‐A induces robust germinal center responses and high affinity antibodies in mice
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DOI: 10.1002/eji.201747113
Abstract: The development of vaccines for infectious diseases for which we currently have none, including HIV, will likely require the use of adjuvants that strongly promote germinal center responses and somatic hypermutation to produce broadly neutralizing… read more here.
Keywords: germinal center; center responses; cell dependent; dotap cpg ... See more keywords