Safety and Response after Peptide Receptor Radionuclide Therapy with 177 Lu-DOTATATE for Neuroendocrine Tumors in Phase 1/2 Prospective Japanese Trial.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of hepato-biliary-pancreatic sciences"
DOI: 10.1002/jhbp.1101
Abstract: BACKGROUND The present prospective phase 1/2 study aimed to elucidate the efficacy and safety of 177 Lu-DOTATATE (four cycles of 7.4 GBq) in Japanese patients with unresectable, progressive neuroendocrine tumors (NETs). METHODS From April 2018… read more here.
Keywords: dotatate; safety; response; neuroendocrine tumors ... See more keywords
Efficacy and safety of 177Lu‑DOTATATE in patients with advanced pancreatic neuroendocrine tumours: data from the NETTER-R international, retrospective study
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-022-05771-3
Abstract: NETTER-R aimed to determine the efficacy, safety and tolerability of 177Lu-DOTATATE in patients with progressive, advanced pancreatic neuroendocrine tumours (panNETs) using retrospective real-world data from multiple sites. This international study retrospectively included patients with panNETs… read more here.
Keywords: dotatate; efficacy safety; dotatate patients; 177lu dotatate ... See more keywords
The utility of 68Gallium-DOTATATE PET/CT in the detection of von Hippel-Lindau disease associated tumors.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of radiology"
DOI: 10.1016/j.ejrad.2018.11.023
Abstract: PURPOSE Patients with von Hippel-Lindau (VHL) disease may develop various tumors, including neuroendocrine tumors of the pancreas (PNETs) and adrenal, central nervous system and retinal hemangioblastomas, kidney tumors and more. 68Ga-DOTATATE positron emission tomography (PET)/computerized… read more here.
Keywords: dotatate pet; detection; von hippel; dotatate ... See more keywords
PET imaging of 52Mn labeled DOTATATE and DOTAJR11
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DOI: 10.1038/s41598-025-85143-7
Abstract: Manganese-52 is gaining interest as an isotope for PET imaging due to its desirable decay and chemical properties for radiopharmaceutical development. Somatostatin receptor 2 (SSTR2) is significantly overexpressed by neuroendocrine tumors (NETs) and is an… read more here.
Keywords: 52mn dotatate; dotatate; 52mn dota; tumor ... See more keywords
Prognostic Utility of Total 68Ga-DOTATATE-Avid Tumor Volume in Patients With Neuroendocrine Tumors.
Sign Up to like & getrecommendations! Published in 2018 at "Gastroenterology"
DOI: 10.1053/j.gastro.2017.11.008
Abstract: BACKGROUND & AIMS Survival times vary among patients with neuroendocrine tumors (NETs) - even among those with the same site, stage, and grade of primary tumor. This makes it difficult to select treatment for patients… read more here.
Keywords: tumor volume; patients neuroendocrine; 68ga dotatate; dotatate ... See more keywords
Cost-effectiveness of Lutetium [177Lu] oxodotreotide versus best supportive care with octreotide in patients with midgut neuroendocrine tumors in France
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DOI: 10.1080/13696998.2020.1830286
Abstract: Abstract Background and aims In France, there are approximately 2,400 new cases of neuroendocrine tumors (NETs) annually. Peptide receptor radionuclide therapy with 177Lu-Dotatate plus long-acting repeatable [LAR] octreotide 30 mg has been shown to significantly improve… read more here.
Keywords: octreotide lar; 177lu dotatate; dotatate; midgut nets ... See more keywords
First in-human study of 64Cu-DOTATATE positron emission tomography/computed tomography(PET/CT) in infective endocarditis: a prospective head-to-head comparison with 18-FDG PET/CT
Sign Up to like & getrecommendations! Published in 2024 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehae666.1814
Abstract: Infective endocarditis (IE) is a severe and potentially fatal condition, which can be challenging to diagnose. Positron emission tomography/computed tomography (PET/CT) with [18F]fluorodeoxyglucose ([18F]FDG) is proposed as a diagnostic tool in the ESC endocarditis guidelines,… read more here.
Keywords: dotatate; 18f fdg; 64cu dotatate; pet ... See more keywords
CTNI-53. SINGLE ARM, OPEN-LABEL, MULTICENTER PHASE II STUDY OF THE RADIONUCLIDE 177LU-DOTATATE (LUTATHERA) IN ADULTS WITH ADVANCED INTRACRANIAL MENINGIOMA
Sign Up to like & getrecommendations! Published in 2020 at "Neuro-oncology"
DOI: 10.1093/neuonc/noaa215.219
Abstract: Meningiomas are the most common primary intracranial neoplasm. Once surgical and radiotherapeutic options are exhausted, there are no effective medical treatments available. A majority of meningiomas express somatostatin receptor 2 (SSTR2), representing a promising treatment… read more here.
Keywords: meningiomas; treatment; 177lu dotatate; dotatate ... See more keywords
IMG-72. [68Ga]Ga-DOTA-TATE PET as imaging biomarker for response assessment and monitoring in patients receiving [177Lu]Lu-DOTA-TATE for advanced intracranial meningioma
Sign Up to like & getrecommendations! Published in 2025 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noaf201.1151
Abstract: [68Ga]Ga-DOTA-TATE (68Ga-Dotatate) PET is a promising imaging modality for post-operative meningioma delineation and outcome assessments following stereotactic radiosurgery. However, its utility for response assessment following other meningioma therapies, including somatostatin receptor 2 (SSTR2) targeting [177Lu]Lu-DOTA-TATE… read more here.
Keywords: dota tate; 68ga dotatate; dotatate; meningioma ... See more keywords
TIP-01. [177Lu]Lu-DOTATATE for recurrent meningioma (LUMEN-1, EORTC-2334-BTG): study protocol for a randomized phase II trial
Sign Up to like & getrecommendations! Published in 2025 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noaf201.1661
Abstract: There are no established treatment options for patients with meningioma recurring after surgery and radiotherapy. Somatostatin receptor type 2 (SSTR2) is highly expressed in meningiomas and SSTR2-targeting radionuclide therapy with [177Lu]Lu-DOTATATE has shown potential activity… read more here.
Keywords: trial; 177lu dotatate; dotatate; 2334 btg ... See more keywords
The therapeutic efficacy of 177Lu-DOTATATE/DOTATOC in advanced neuroendocrine tumors
Sign Up to like & getrecommendations! Published in 2020 at "Medicine"
DOI: 10.1097/md.0000000000019304
Abstract: Abstract Background: Somatostatin analog therapies showed great potential for patients suffering advanced neuroendocrine tumors (NETs). This study was aimed to evaluate the therapeutic efficacy of 177Lu-DOTATATE/DOTATOC (177Lu-octreotate/octreotide) peptide receptor radionuclide therapy (PRRT) in advanced or… read more here.
Keywords: dotatate; therapeutic efficacy; advanced neuroendocrine; response ... See more keywords