Evaluation of 68Ga-DOTATATE uptake at the pituitary region and the biochemical response to somatostatin analogs in acromegaly
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Endocrinological Investigation"
DOI: 10.1007/s40618-021-01523-6
Abstract: Acromegaly is associated with many comorbidities and increased mortality. The first-line treatment is transsphenoidal surgery. However, many patients also need adjuvant drug treatment after surgery. Somatostatin analog (SSA), which suppresses GH secretion by somatotrophs by… read more here.
Keywords: response; treatment; dotatate uptake; pituitary region ... See more keywords
68Ga-DOTATATE Uptake in Pancreatic Metastasis of Renal Cell Carcinoma Mimicking Pancreatic Neuroendocrine Tumor.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Nuclear Medicine"
DOI: 10.1097/rlu.0000000000002718
Abstract: A 61-year-old man, with a history of prior clear cell renal cell carcinoma in remission, was referred to Ga-DOTATATE PET/CT for the further evaluation of pancreatic tail mass. Ga-DOTATATE PET/CT showed pathologically intense uptake on… read more here.
Keywords: renal cell; cell; dotatate uptake; cell carcinoma ... See more keywords
64Cu-DOTATATE Uptake in a Pulmonary Hamartoma.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical nuclear medicine"
DOI: 10.1097/rlu.0000000000004390
Abstract: ABSTRACT DOTATATE PET/CT is frequently used to evaluate indeterminant pulmonary nodules suspected to be pulmonary carcinoid. We report an unexpected case of pulmonary hamartoma demonstrating 64Cu-DOTATATE uptake in a 43-year-old woman with a slowly enlarging… read more here.
Keywords: uptake pulmonary; dotatate; 64cu dotatate; dotatate uptake ... See more keywords
Increased 68Ga-DOTATATE Uptake in Supraclavicular Brown Adipose Tissue.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical nuclear medicine"
DOI: 10.1097/rlu.0000000000004405
Abstract: ABSTRACT Characterization of brown adipose tissue (BAT) 18F-FDG uptake has been well reported; however, 68Ga-DOTA-conjugated somatostatin receptor targeting peptides uptake in BAT is rarely documented. Herein, we report an interesting case of increased 68Ga-DOTATATE uptake… read more here.
Keywords: adipose tissue; 68ga dotatate; uptake supraclavicular; increased 68ga ... See more keywords
The Effect of VPA Treatment on Radiolabeled DOTATATE Uptake: Differences Observed In Vitro and In Vivo
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14010173
Abstract: Background: To improve peptide receptor radionuclide therapy (PRRT), we aimed to enhance the expression of somatostatin type-2 receptors (SSTR2) in vitro and in vivo, using valproic acid (VPA). Methods: Human NCI-H69 small-cell lung carcinoma cells… read more here.
Keywords: vitro vivo; vpa; 177lu dotatate; sstr2 expression ... See more keywords