Double dose alglucosidase-alpha doubles benefit?
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Genetics and Metabolism Reports"
DOI: 10.1016/j.ymgmr.2018.07.004
Abstract: We read with interst the article by Landis et al. about a 3 monthsold male with dilated cardiomyopathy due to infantile onset Pompe disease (IOPD) who profited from increased dosage of algucosidase-alpha (40mg/kg/d twice a… read more here.
Keywords: index; dose alglucosidase; case; double dose ... See more keywords
Ezetimibe plus statin combination versus double-dose statin in patients with dyslipidemia and atherosclerotic cardiovascular disease risk: a comprehensive systematic review and meta-analysis of 47 randomized controlled trials
Sign Up to like & getrecommendations! Published in 2025 at "Baylor University Medical Center Proceedings"
DOI: 10.1080/08998280.2025.2487966
Abstract: Abstract Background Dyslipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Oral regimens to achieve blood lipid targets include increasing the statin dose or adding ezetimibe to statin therapy. The optimal strategy remains… read more here.
Keywords: dose statin; plus statin; risk; double dose ... See more keywords
Time to Change Dosing of Inactivated Quadrivalent Influenza Vaccine in Young Children: Evidence From a Phase III, Randomized, Controlled Trial
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the Pediatric Infectious Diseases Society"
DOI: 10.1093/jpids/piw068
Abstract: Abstract Background. Children under 3 years of age may benefit from a double-dose of inactivated quadrivalent influenza vaccine (IIV4) instead of the standard-dose. Methods. We compared the only United States-licensed standard-dose IIV4 (0.25 mL, 7.5… read more here.
Keywords: influenza; double dose; vaccine; dose iiv4 ... See more keywords
592. Immunogenicity and Safety of High-dose versus Double-dose Quadrivalent Inactivated Influenza Vaccine in Adult Kidney Transplant Recipients: A Randomized Controlled Trial
Sign Up to like & getrecommendations! Published in 2025 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofae631.187
Abstract: Abstract Background Both high-dose and double-dose inactivated influenza vaccines have been shown to better elicit a greater immune response compared to standard-dose influenza vaccine in solid organ transplant (SOT) recipients. However, a direct comparison between… read more here.
Keywords: qiiv; high dose; double dose; qiiv group ... See more keywords
Abstract 4138221: Ezetimibe plus statin combination vs. double dose statin for patients with dyslipidemia and ASCVD risk: A Systematic Review and Meta-Analysis
Sign Up to like & getrecommendations! Published in 2024 at "Circulation"
DOI: 10.1161/circ.150.suppl_1.4138221
Abstract: Background: Dyslipidemia is a major risk factor for Atherosclerotic Cardiovascular Disease (ASCVD). Statin is a crucial intervention to fix dyslipidemia and reduce the ASCVD risk. Still, there are several regimens to achieve blood lipid level… read more here.
Keywords: dose statin; double dose; statin; ascvd risk ... See more keywords
Prime-boost, double-dose influenza vaccine immunity in COPD: a pilot observational study
Sign Up to like & getrecommendations! Published in 2022 at "ERJ Open Research"
DOI: 10.1183/23120541.00641-2021
Abstract: Background COPD patients are more susceptible to viral respiratory infections and their sequelae, and have intrinsically weaker immune responses to vaccinations against influenza and other pathogens. Prime-boost, double-dose immunisation has been suggested as a general… read more here.
Keywords: copd; boost double; prime boost; double dose ... See more keywords
The dose effectiveness of extracorporeal shockwave on plantar flexor spasticity of ankle in stroke patients: a randomized controlled trial
Sign Up to like & getrecommendations! Published in 2024 at "Journal of NeuroEngineering and Rehabilitation"
DOI: 10.1186/s12984-024-01473-z
Abstract: Extracorporeal shockwave therapy (ESWT) has been proven beneficial for post-stroke spasticity (PSS) of ankle plantar flexor muscles. This study aims to investigate the dose-response effectiveness of focused-ESWT and the duration of its effect on the… read more here.
Keywords: plantar flexor; dose eswt; stroke patients; group ... See more keywords
Safety and efficacy of immunotherapy using a double-dose regimen in advanced non-small cell lung cancer (NSCLC): results of IDEE study
Sign Up to like & getrecommendations! Published in 2024 at "Translational Lung Cancer Research"
DOI: 10.21037/tlcr-24-141
Abstract: Background Pembrolizumab 400 mg every six weeks (Q6W) and nivolumab 480 mg every four weeks (Q4W) are used since 2020 and the coronavirus disease 2019 (COVID-19) pandemic. This recommendation relied on pharmacokinetic and pharmacodynamic models.… read more here.
Keywords: lung cancer; efficacy; double dose; cell ... See more keywords
Double dose of 5-aminolevulinic acid and its effect on protoporphyrin IX accumulation in low-grade glioma.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of neurosurgery"
DOI: 10.3171/2021.12.jns211724
Abstract: OBJECTIVE Administration of 5-aminolevulinic acid (5-ALA) does not regularly elicit fluorescence in low-grade glioma (LGG) at currently established doses and timing of administration. One explanation may be differences in blood-brain barrier (BBB) integrity compared to… read more here.
Keywords: low grade; glioma; grade; aminolevulinic acid ... See more keywords
Simultaneous Double Dose Measurements Using TLD-100H
Sign Up to like & getrecommendations! Published in 2024 at "Crystals"
DOI: 10.3390/cryst14070603
Abstract: Thermoluminescent dosimeters (TLD) and optically stimulated luminescent dosimeters (OSLD) are practical, accurate, and precise tools for point dosimetry in medical physics applications. The objective of this study is to investigate the luminescence properties—both OSL and… read more here.
Keywords: measurements using; dose measurements; using tld; double dose ... See more keywords
Neuroprotective Effects of Erinacine A on an Experimental Model of Traumatic Optic Neuropathy
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24021504
Abstract: Erinacine A (EA), a natural neuroprotectant, is isolated from a Chinese herbal medicine, Hericium erinaceus. The aim of this study was to investigate the neuroprotective effects of EA in a rat model of traumatic optic… read more here.
Keywords: standard dose; treated group; neuroprotective effects; group ... See more keywords