Preparation and characterization of liposomes double loaded with amphotericin B and amphotericin B/hydroxypropyl-beta-cyclodextrin inclusion complex.
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceutical nanotechnology"
DOI: 10.2174/2211738509666210310160436
Abstract: BACKGROUND Amphotericin B (AMB) is water-insoluble polyene, which has a broad spectrum of antifungal activity. The hydrophobic drug only exits in the phospholipid bilayer, leading to a low-drug liposomal loading capacity. OBJECTIVES This study is… read more here.
Keywords: amphotericin; liposomes double; double loaded; drug ... See more keywords
Double-Loaded Doxorubicin/Resveratrol Polymeric Micelles Providing Low Toxicity on Cardiac Cells and Enhanced Cytotoxicity on Lymphoma Cells
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics15041287
Abstract: The anthracycline antibiotic doxorubicin is a well-known antitumour agent, however its cardiotoxicity is a significant obstacle to therapy. The aim of the present study was to improve the safety of doxorubicin through its simultaneous encapsulation… read more here.
Keywords: loaded micelles; cytotoxicity; resveratrol; lymphoma cells ... See more keywords