Clinical characteristics of double negative atypical inflammatory demyelinating disease: A prospective study
Sign Up to like & getrecommendations! Published in 2024 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.52191
Abstract: This study aimed to investigate the clinical characteristics and predictors of relapse in double negative atypical inflammatory demyelinating disease (IDD) and to explore potential antigenic targets by tissue‐based assays (TBA) using rat brain indirect immunofluorescence. read more here.
Keywords: clinical characteristics; atypical inflammatory; double negative; inflammatory demyelinating ... See more keywords
Detection of signature double‐negative T cells is a predictive marker to identify autoimmune lymphoproliferative syndrome associated with FAS loss of function
Sign Up to like & getrecommendations! Published in 2024 at "American Journal of Hematology"
DOI: 10.1002/ajh.27286
Abstract: The autoimmune lymphoproliferative syndrome (ALPS) is caused by defects in the FAS-dependent apoptosis leading to chronic lymphoproliferation, autoimmunity, chronic multilineage cytopenia, an increased risk for developing B cell lymphomas, and a characteristic accumulation of CD4/CD8-negative,… read more here.
Keywords: double negative; function; detection signature; autoimmune lymphoproliferative ... See more keywords
Double Negative Control Inference With Some Invalid Negative Control Exposures for Continuous Outcome
Sign Up to like & getrecommendations! Published in 2025 at "Statistics in Medicine"
DOI: 10.1002/sim.70276
Abstract: Negative controls have been increasingly used for causal inference when unmeasured confounding exist. Valid negative control exposures (NCEs) could not causally affect outcome, and valid negative control outcomes (NCOs) are not to be causally affected… read more here.
Keywords: invalid negative; negative control; control; double negative ... See more keywords
Severity of SARS-CoV-2 infection is linked to double-negative (CD27− IgD−) B cell subset numbers
Sign Up to like & getrecommendations! Published in 2021 at "Inflammation Research"
DOI: 10.1007/s00011-021-01525-3
Abstract: Objectives The role of B cells in COVID‐19, beyond the production of specific antibodies against SARS-CoV-2, is still not well understood. Here, we describe the novel landscape of circulating double-negative (DN) CD27 − IgD −… read more here.
Keywords: sars cov; negative cd27; double negative; cd27 igd ... See more keywords
Double-negative T cells with a distinct transcriptomic profile are abundant in the peripheral blood of patients with breast cancer
Sign Up to like & getrecommendations! Published in 2024 at "Breast Cancer Research and Treatment"
DOI: 10.1007/s10549-024-07477-6
Abstract: Double-negative T (DNT) cells comprise a distinct subset of T lymphocytes that have been implicated in immune responses. The aim of this study was to characterize the peripheral DNT population in breast cancer (BC) patients.… read more here.
Keywords: peripheral blood; breast cancer; double negative; dnt cells ... See more keywords
Nonspecific increase of αβTCR+ double-negative T cells in pediatric rheumatic diseases
Sign Up to like & getrecommendations! Published in 2024 at "World Journal of Pediatrics"
DOI: 10.1007/s12519-024-00854-7
Abstract: An increased number of double-negative T (DNT) cells expressing the αβ T cell receptor (αβ+DNT cells) is one of the diagnostic criteria for autoimmune lymphoproliferative syndrome (ALPS). Moreover, these cells are expanded in a widely… read more here.
Keywords: double negative; pediatric rheumatic; dnt cells; dnt ... See more keywords
Design and analysis of a new composite double negative metamaterial for multi-band communication
Sign Up to like & getrecommendations! Published in 2017 at "Current Applied Physics"
DOI: 10.1016/j.cap.2017.04.008
Abstract: Abstract In this paper, a double C-shaped structure of double negative composite metamaterial is designed and depicts in configurations that can capable in a multi-band microwave frequency band. The design has achieved relative negative permeability,… read more here.
Keywords: negative metamaterial; double negative; multi band; band ... See more keywords
Cell Competition, the Kinetics of Thymopoiesis, and Thymus Cellularity Are Regulated by Double-Negative 2 to 3 Early Thymocytes.
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.107910
Abstract: Cell competition in the thymus is a homeostatic process that drives turnover. If the process is impaired, thymopoiesis can be autonomously maintained for several weeks, but this causes leukemia. We aimed to understand the effect… read more here.
Keywords: cell competition; cell; kinetics thymopoiesis; double negative ... See more keywords
Topology optimization of anisotropic broadband double-negative elastic metamaterials
Sign Up to like & getrecommendations! Published in 2017 at "Journal of The Mechanics and Physics of Solids"
DOI: 10.1016/j.jmps.2017.04.009
Abstract: Abstract As the counterpart of electromagnetic and acoustic metamaterials, elastic metamaterials are artificial periodic elastic composite materials offering the possibility to manipulate elastic wave propagation in the subwavelength scale through different mechanisms. For the promising… read more here.
Keywords: negative effective; anisotropic; double negative; topology ... See more keywords
The double negative: Personality differentially predicts sensitivity to need support and thwarting, and subsequent behavioural response planning
Sign Up to like & getrecommendations! Published in 2020 at "Personality and Individual Differences"
DOI: 10.1016/j.paid.2019.109767
Abstract: Abstract Research extending self-determination theory (SDT) recognises that individual differences alter responses to basic psychological need thwarting or supportive environments. Here, two underlying pathways were proposed and tested, namely whether personality alters: (i) sensitivity to… read more here.
Keywords: response; support thwarting; double negative; sensitivity ... See more keywords
Decreased IgD- CD27- double negative B cells in Sjögren’s disease correlated with disease activity index
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-19796-9
Abstract: Double negative (DN) B cells, defined as CD27-IgD- B cells, are increased in older healthy individuals as well as in patients with certain diseases. However, the relationship between DN B cells and Sjögren’s disease (SjD)… read more here.
Keywords: disease; disease activity; cells gren; negative cells ... See more keywords