Novel POFUT1 mutation associated with hidradenitis suppurativa–Dowling–Degos disease firm up a role for Notch signalling in the pathogenesis of this disorder: reply from the authors
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DOI: 10.1111/bjd.16274
Abstract: O-fucosyltransferase 1, cause generalized Dowling-Degos disease. Am J Hum Genet 2013; 92:895–903. 3 McMillan BJ, Zimmerman B, Egan ED et al. Structure of human POFUT1, its requirement in ligand-independent oncogenic Notch signaling, and functional effects… read more here.
Keywords: degos disease; novel pofut1; pofut1 mutation; mutation associated ... See more keywords
Mast cell activation in Dowling–Degos disease
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DOI: 10.1111/bjd.18221
Abstract: Dowling-Degos disease (DDD OMIM 179850) is a rare autosomal-dominant genodermatosis in the spectrum of reticulate pigmented anomalies that usually presents after puberty. It is characterised by reticulate hyperpigmentation and small brownish papules, located at various… read more here.
Keywords: degos disease; activation dowling; cell activation; mast cell ... See more keywords
Successful Management of Dowling-Degos Disease with Combination of Q-switched Nd: YAG and Fractional Carbon Dioxide Laser
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DOI: 10.4103/0974-2077.204583
Abstract: Journal of Cutaneous and Aesthetic Surgery ¦ Volume 10 ¦ Issue 1 ¦ January‐March 2017 60 Subungual SCC is a low‐grade malignant tumour with >150 cases reported in literature. It may arise from nail bed,… read more here.
Keywords: degos disease; disease combination; nail; management dowling ... See more keywords
Dermoscopy of Follicular Dowling–Degos Disease
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DOI: 10.4103/ijd.ijd_260_18
Abstract: Dowling–Degos disease (DDD) is a late-onset genodermatosis characterized by hyperpigmented macules on the flexures along with scattered comedo-like lesions and pitted acneiform scars. Follicular Dowling–Degos is a rare type of DDD, with only two reports… read more here.
Keywords: degos disease; like lesions; comedo like; follicular dowling ... See more keywords
Dowling–Degos Disease with Follicular Involvement Associated with Hidradenitis Suppurativa: A Manifestation of Follicular Occlusion Phenomenon?
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DOI: 10.4103/ijd.ijd_392_18
Abstract: A 30-year-old female patient presented with progressive reticulate pigmentation of the neck, upper chest, back, cubital fossa, and axillae since the age of 15 years. The patient also complained of recurrent multiple tender nodules and… read more here.
Keywords: hidradenitis suppurativa; follicular involvement; degos disease; dowling degos ... See more keywords
Generalized Dowling–Degos disease with hypopigmented lesions: A diagnostic challenge
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DOI: 10.4103/ijdvl.ijdvl_153_17
Abstract: Sir, Dowling–Degos disease (DDD) is a rare autosomal dominant, progressive, reticulate pigmentary disorder. It usually appears after puberty.It is clinically characterized by hyperpigmented macules, papules and comedone‐like lesions on flexures and perioral pitted scars.1,2 The… read more here.
Keywords: generalized dowling; degos disease; disease hypopigmented; hypopigmented lesions ... See more keywords