MYC is downregulated by a mitochondrial checkpoint mechanism
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DOI: 10.18632/oncotarget.21653
Abstract: The MYC proto-oncogene serves as a rheostat coupling mitogenic signaling with the activation of genes regulating growth, metabolism and mitochondrial biogenesis. Here we describe a novel link between mitochondria and MYC levels. Perturbation of mitochondrial… read more here.
Keywords: mechanism; mitochondrial checkpoint; downregulated mitochondrial; myc downregulated ... See more keywords