Articles with "downregulating snare" as a keyword



Elevated PEDF promotes the occurrence of diabetes mellitus via suppressing GSIS by downregulating the SNARE complex

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Published in 2025 at "Communications Biology"

DOI: 10.1038/s42003-025-09061-0

Abstract: Type 2 diabetes mellitus (T2DM) is a major global public health burden. The mechanisms through which glucose-stimulated insulin secretion (GSIS) can be suppressed in individuals with obesity-derived type 2 diabetes mellitus (T2DM) have not been… read more here.

Keywords: pedf; snare complex; diabetes mellitus; downregulating snare ... See more keywords