Downregulation of miR‐1224 protects against oxidative stress‐induced acute liver injury by regulating hepatocyte growth factor
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28502
Abstract: To study the effect of microRNA‐1224 (miR‐1224) on hydrogen peroxide (H2O 2)‐induced oxidative stress injury in hepatocytes, and explore its underlying mechanism. read more here.
Keywords: injury; mir 1224; downregulation mir; oxidative stress ... See more keywords
The downregulation of miR‐22 and miR‐372 may contribute to gestational diabetes mellitus through regulating glucose metabolism via the PI3K/AKT/GLUT4 pathway
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24557
Abstract: Identifying effective regulatory mechanisms will be significant for Gestational diabetes mellitus (GDM) diagnosis and treatment. read more here.
Keywords: mir 372; downregulation mir; gestational diabetes; diabetes mellitus ... See more keywords
Aberrant ERG expression associates with downregulation of miR‐4638‐5p and selected genomic alterations in a subset of diffuse large B‐cell lymphoma
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23074
Abstract: ERG (avian v‐ets erythroblastosis virus E26 oncogene homolog), an oncoprotein in prostate carcinoma and Ewing's sarcoma is associated with poor prognosis in patients with acute myeloid leukemia and T lymphoblastic leukemia. However little is known… read more here.
Keywords: dlbcl; erg; expression; cell ... See more keywords
Downregulation of miR-133a contributes to the cardiac developmental toxicity of trichloroethylene in zebrafish.
Sign Up to like & getrecommendations! Published in 2020 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2020.126610
Abstract: Trichloroethylene (TCE), a widely used organic solvent, is a common environmental pollutant. Increasing evidence indicates that maternal TCE exposure is associated with congenital cardiac defects, but the underlining mechanisms remain largely unknown. In this study,… read more here.
Keywords: heart; tce; trichloroethylene; mir 133a ... See more keywords
Downregulation of miR-383 reduces depression-like behavior through targeting Wnt family member 2 (Wnt2) in rats
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-88560-6
Abstract: This study aimed to evaluate the role of miR-383 in the regulation of Wnt-2 signaling in the rat model of chronic stress. The male SD rats with depressive-like behaviors were stimulated with chronic unpredictable mild… read more here.
Keywords: depression; wnt family; wnt2; expression levels ... See more keywords
Downregulation of miR-527 alleviates sepsis-induced acute kidney injury via targeting Beclin1.
Sign Up to like & getrecommendations! Published in 2022 at "Histology and histopathology"
DOI: 10.14670/hh-18-531
Abstract: BACKGROUND Sepsis-induced acute kidney injury (AKI) is known to result from the inflammatory responses. MiRNAs participate in the development of sepsis-induced AKI. Nevertheless, the function of miR-527 in sepsis-induced AKI remains unclear. METHODS Cell viability… read more here.
Keywords: sepsis induced; mir 527; induced aki; downregulation mir ... See more keywords
Downregulation of miR-199a-5p promotes prostate adeno-carcinoma progression through loss of its inhibition of HIF-1α
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.18315
Abstract: Hypoxia-inducible factor-1 alpha (HIF-1α) plays key roles in cell survival under both hypoxia and normoxia conditions. Regulation of HIF-1α is complex and involves numerous molecules and pathways, including post-transcriptional regulation by microRNAs (miRNAs). Although upregulation… read more here.
Keywords: hif; promotes prostate; 199a promotes; mir 199a ... See more keywords