Downregulation of PARP1 transcription by promoter-associated E2F4-RBL2-HDAC1-BRM complex contributes to repression of pluripotency stem cell factors in human monocytes
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DOI: 10.1038/s41598-017-10307-z
Abstract: Differentiation of certain cell types is followed by a downregulation of PARP1 expression. We show that the reduction in the abundance of PARP1 in hematopoietic progenitor cells and monocytes is tightly controlled by the cell… read more here.
Keywords: transcription; downregulation parp1; hdac1; parp1 ... See more keywords