Methods for Eluting Intact Extracellular Vesicles From Aptamer‐Based Affinity Chromatography: A Critical Evaluation Based on Downstream Applications
Sign Up to like & getrecommendations! Published in 2025 at "Biotechnology Journal"
DOI: 10.1002/biot.202400648
Abstract: Extracellular vesicles (EVs) are nanosized vesicles released by cells, containing molecular cargo such as proteins and nucleic acids. EVs offer promising avenues for the detection of biomarkers of disease and are excellent candidates for drug… read more here.
Keywords: extracellular vesicles; intact evs; elution; downstream applications ... See more keywords
Preanalytical DNA assessment for downstream applications: How to optimize the management of human biospecimens to support molecular diagnosis—An experimental study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24531
Abstract: The development of next‐generation sequencing approaches has accelerated the diagnostic process, although at present, there is a lack of a clear consensus on efficient management of human samples for downstream applications. This study aims to… read more here.
Keywords: human biospecimens; preanalytical dna; downstream applications; management human ... See more keywords
Two-dimensional layered material photodetectors: what could be the upcoming downstream applications beyond prototype devices?
Sign Up to like & getrecommendations! Published in 2024 at "Nanoscale horizons"
DOI: 10.1039/d4nh00170b
Abstract: With distinctive advantages spanning excellent flexibility, rich physical properties, strong electrostatic tunability, dangling-bond-free surface, and ease of integration, 2D layered materials (2DLMs) have demonstrated tremendous potential for photodetection. However, to date, most of the research… read more here.
Keywords: dimensional layered; downstream applications; downstream; two dimensional ... See more keywords
Abstract 1991: Exploring the potential of exosomes for cancer diagnosis and management: Comparative analysis of isolation methods for optimum yield purity and downstream applications
Sign Up to like & getrecommendations! Published in 2019 at "Tumor Biology"
DOI: 10.1158/1538-7445.am2019-1991
Abstract: Exosomes have received significant attention due to their involvement in several diseases, including cancer, and are being explored as a tool for disease diagnosis and management. As a result, several kits based on different principles… read more here.
Keywords: downstream applications; yield; cancer; diagnosis management ... See more keywords
Protein purification strategies must consider downstream applications and individual biological characteristics
Sign Up to like & getrecommendations! Published in 2022 at "Microbial Cell Factories"
DOI: 10.1186/s12934-022-01778-5
Abstract: Background Proteins are used as reagents in a broad range of scientific fields. The reliability and reproducibility of experimental data will largely depend on the quality of the (recombinant) proteins and, consequently, these should undergo… read more here.
Keywords: downstream applications; purification strategies; characteristics protein; protein purification ... See more keywords