Histone deacetylase inhibitor CI‐994 inhibits osteoclastogenesis via suppressing NF‐&kgr;B and the downstream c‐Fos/NFATc1 signaling pathways
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2019.01.021
Abstract: &NA; [4‐(acetylamino)‐N‐(2‐amino‐phenyl) benzamide] (CI‐994) is a histone deacetylase 1‐3 specific inhibitor that has been shown to indirectly increase the production of Dickkopf‐1, which is an inhibitor of osteoclastic development. However, whether CI‐994 has an influence… read more here.
Keywords: inhibitor; fos nfatc1; fos; downstream fos ... See more keywords