Characterization of low-dose doxorubicin-loaded silica-based nanocomposites
Sign Up to like & getrecommendations! Published in 2018 at "Applied Surface Science"
DOI: 10.1016/j.apsusc.2017.08.006
Abstract: Abstract In this study, we synthesized multicomponent solid films of low-dose doxorubicin (DOX)-loaded polydimethylsiloxane (PDMS)-SiO 2 /CaP nanocomposites via sol–gel process combined with the method of evaporation-induced self-assembly (EISA) at low temperature. Nanomechanical properties (elasticity… read more here.
Keywords: low dose; dox loaded; dose doxorubicin; dox ... See more keywords
NIR-laser switched ICG/DOX loaded thermo-responsive polymeric capsule for chemo-photothermal targeted therapy
Sign Up to like & getrecommendations! Published in 2017 at "European Polymer Journal"
DOI: 10.1016/j.eurpolymj.2017.04.019
Abstract: Abstract Near-infrared (NIR) light possesses great advantages for light-responsive controllable drug release, such as deep tissue penetration and low damage to healthy tissues. Herein, a targeted and NIR-triggered drug delivery system is developed based on… read more here.
Keywords: thermo responsive; loaded thermo; capsule; drug ... See more keywords
99mTc-Doxorubicin-loaded gallic acid-gold nanoparticles (99mTc-DOX-loaded GA-Au NPs) as a multifunctional theranostic agent.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2020.119514
Abstract: The development of cancer theranostic nanomedicines is recommended to concurrently achieve and evaluate the therapeutic benefit and progress. The current work aims to develop gallic acid-gold nanoparticles (GA-Au NPs) as a theranostic probe for 99mTc-Doxorubicin… read more here.
Keywords: agent; gallic acid; dox loaded; 99mtc dox ... See more keywords
Photochemical internalization enhanced macrophage delivered chemotherapy.
Sign Up to like & getrecommendations! Published in 2018 at "Photodiagnosis and photodynamic therapy"
DOI: 10.1016/j.pdpdt.2017.12.002
Abstract: BACKGROUND Macrophage (Ma) vectorization of chemotherapeutic drugs has the advantage for cancer therapy in that it can actively target and maintain an elevated concentration of drugs at the tumor site, preventing their spread into healthy… read more here.
Keywords: drug; dox loaded; photochemical internalization; dox ... See more keywords
The Formation of Self-Assembled Nanoparticles Loaded with Doxorubicin and d-Limonene for Cancer Therapy
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c04238
Abstract: Self-assembled nanoparticles present unique properties that have potential applications in the development of a successful drug delivery system. Doxorubicin (DOX) is an important anti-neoplastic anthracycline chemotherapeutic drug widely described. However, it suffers from serious dose-dependent… read more here.
Keywords: dox; limonene; self assembled; activity ... See more keywords
Doxorubicin-loaded platelets as a smart drug delivery system: An improved therapy for lymphoma
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep42632
Abstract: Chemotherapy is majorly used for the treatment of many cancers, including lymphoma. However, cytotoxic drugs, utilized in chemotherapy, can induce various side effects on normal tissues because of their non-specific distribution in the body. Natural… read more here.
Keywords: lymphoma; loaded platelets; drug; dox loaded ... See more keywords
Local penetration of doxorubicin via intrahepatic implantation of PLGA based doxorubicin-loaded implants
Sign Up to like & getrecommendations! Published in 2019 at "Drug Delivery"
DOI: 10.1080/10717544.2019.1676842
Abstract: Abstract Doxorubicin (DOX) is widely used in the chemotherapy of a wide range of cancers. However, intravenous administration of DOX causes toxicity to most major organs which limits its clinical application. DOX-loaded drug delivery system… read more here.
Keywords: loaded implants; drug; dox loaded; dox ... See more keywords
Liposomal Doxorubicin: the Sphingomyelin/Cholesterol System Significantly Enhances the Antitumor Efficacy of Doxorubicin
Sign Up to like & getrecommendations! Published in 2023 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-022-02489-1
Abstract: Doxorubicin (DOX) has a cytotoxic effect on many tumor cells; however, its clinical application is limited owing to its strong side effects. Although Doxil® reduces the cardiotoxicity of free DOX, it has also introduced a… read more here.
Keywords: system; antitumor; effect; dox ... See more keywords
Decapeptide functionalized targeted mesoporous silica nanoparticles with doxorubicin exhibit enhanced apoptotic effect in breast and prostate cancer cells
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s184634
Abstract: Background Considering the increase in cancer cases and number of deaths per year worldwide, development of potential therapeutics is imperative. Mesoporous silica nanoparticles (MSNPs) are among the potential nanocarriers having unique properties for drug delivery.… read more here.
Keywords: microscopy; msnps; dox loaded; dox ... See more keywords
pH-Responsive Hybrid Nanoassemblies for Cancer Treatment: Formulation Development, Optimization, and In Vitro Therapeutic Performance
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics15020326
Abstract: Current needs for increased drug delivery carrier efficacy and specificity in cancer necessitate the adoption of intelligent materials that respond to environmental stimuli. Therefore, we developed and optimized pH-triggered drug delivery nanoassemblies that exhibit an… read more here.
Keywords: cell; dox; loaded lnlcs; dox loaded ... See more keywords