Development of anticancer peptides with low hemolysis, high penetrating membrane activity, certain analgesic activity and the synergistic anticancer effect.
Sign Up to like & getrecommendations! Published in 2022 at "Biomaterials science"
DOI: 10.1039/d1bm02024b
Abstract: Herein, an amphiphilic cationic α-helical anticancer lipopeptide, P10 with low toxicity and high penetrating membrane activity was developed. This lipopeptide could self-assemble into stable spherical aggregates in aqueous solution and encapsulate Dox with a hydrophobic… read more here.
Keywords: dox nanomedicine; p10 dox; anticancer; activity ... See more keywords
Preparation of β-CD-LA aggregate and its application as drug carriers
Sign Up to like & getrecommendations! Published in 2019 at "Materials Technology"
DOI: 10.1080/10667857.2019.1611054
Abstract: ABSTRACT Linoleic acid (LA) and β-CD-NH2 molecule are covalently conjugated to form a β-CD-LA molecule. The β-CD-LA molecule can self-assemble into spherical micelles with an average particle size of about 50.75±13.58 nm, which is beneficial… read more here.
Keywords: dox nanomedicine; preparation aggregate; experiments show; drug ... See more keywords