Shear-responsive injectable supramolecular hydrogel releasing doxorubicin loaded micelles with pH-sensitivity for local tumor chemotherapy.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2017.07.063
Abstract: In this study, glycol chitosan-Pluronic F127 conjugate (GC-PF127), produced by an amidation reaction between terminal-carboxylated PF127 and glycol chitosan (GC), was used to prepare doxorubicin (DOX)-loaded micelles. The DOX/GC-PF127 micelles produced at optimal conditions had… read more here.
Keywords: hydrogel; shear responsive; dox pf127; loaded micelles ... See more keywords