Mesenchymal stem cells anchored with thymidine phosphorylase for doxifluridine-mediated cancer therapy
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DOI: 10.1039/d0ra10263f
Abstract: Many tumors express thymidine phosphorylase (TYMP) with various levels, however due to tumor heterogeneity, the amount of TYMP is usually not enough to convert prodrug doxifluridine (5′-DFUR) to toxic drug 5-fluorouracil (5-FU). Since human mesenchymal… read more here.
Keywords: thymidine phosphorylase; doxifluridine; cancer; stem cells ... See more keywords