Fucoidan Protects against Doxorubicin-Induced Cardiotoxicity by Reducing Oxidative Stress and Preventing Mitochondrial Function Injury
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DOI: 10.3390/ijms231810685
Abstract: Doxorubicin (DOXO) is a potent chemotherapeutic drug widely used to treat various cancers. However, its clinical application is limited due to serious adverse effects on dose-dependent cardiotoxicity. Although the underlying mechanism has not been fully… read more here.
Keywords: induced cardiotoxicity; doxo induced; cardiotoxicity; fucoidan ... See more keywords
Simvastatin Reduces Doxorubicin-Induced Cardiotoxicity: Effects beyond Its Antioxidant Activity
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DOI: 10.3390/ijms24087573
Abstract: This study aimed to evaluate if Simvastatin can reduce, and/or prevent, Doxorubicin (Doxo)-induced cardiotoxicity. H9c2 cells were treated with Simvastatin (10 µM) for 4 h and then Doxo (1 µM) was added, and the effects… read more here.
Keywords: calcium; induced cardiotoxicity; doxo induced; doxo ... See more keywords