Efficacious Doxorubicin Delivery Using Glutathione‐Responsive Hollow Non‐phospholipid Vesicles Bearing Lipoyl Cholesterols
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DOI: 10.1002/cmdc.201900335
Abstract: In this study, we developed redox‐sensitive vesicles using synthesised lipoyl cholesterol derivatives, a non‐ionic surfactant and an optimum level of free cholesterol. Interestingly, concentration‐dependent self‐assembly was observed by scanning electron microscopy, wherein vesicles manifested as… read more here.
Keywords: efficacious doxorubicin; drug; doxorubicin delivery; delivery using ... See more keywords
Reduction‐Triggered Doxorubicin Delivery by Self‐Assembled Nanospheres of Lipoylated Caffeine
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DOI: 10.1002/cmdc.202000070
Abstract: This study reports a new amphiphilic bioconjugate (CAFF‐LA) derived from the lipoylation of a hydroxyethyl derivative of caffeine. In water, CAFF‐LA self‐assembles into nanospheres with an average size of 155 nm, as evidenced from dynamic light… read more here.
Keywords: reduction; triggered doxorubicin; doxorubicin delivery; reduction triggered ... See more keywords
Hyaluronan-Cyclodextrin Conjugates as Doxorubicin Delivery Systems
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DOI: 10.3390/pharmaceutics15020374
Abstract: In the last years, nanoparticles based on cyclodextrins have been widely investigated for the delivery of anticancer drugs. In this work, we synthesized nanoparticles with a hyaluronic acid backbone functionalized with cyclodextrins under green conditions.… read more here.
Keywords: hyaluronan cyclodextrin; delivery systems; doxorubicin delivery; cyclodextrin conjugates ... See more keywords