Simultaneous proteasome and autophagy inhibition synergistically enhances cytotoxicity of doxorubicin in breast cancer cells
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3704
Abstract: Ubiquitin–proteasome system (UPS) and autophagy are interconnected proteolysis pathways implicated in doxorubicin resistance of breast cancer cells. Following anticancer treatments, autophagy either plays a cytoprotective role or augments treatment‐induced cytotoxicity. However, the role of autophagy… read more here.
Keywords: doxorubicin ixazomib; breast cancer; cancer cells; doxorubicin ... See more keywords