Vincristine-doxorubicin co-loaded artificial low-density lipoproteins towards solid tumours.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2021.113802
Abstract: To construct an artificial low-density lipoprotein (aLDL) that highly mimics low-density lipoprotein (LDL) in vivo, and deliver vincristine (VCR) - doxorubicin (DOX) simultaneously, the 100 nm and 35 nm DOX-VCR-aLDLs (DV-aLDLs) were constructed, then the physicochemical characteristics were… read more here.
Keywords: vincristine doxorubicin; artificial low; density; low density ... See more keywords
Multifunctional doxorubicin‐loaded magnetoliposomes with active and magnetic targeting properties
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ejps.2018.07.044
Abstract: ABSTRACT Multifunctional magnetoliposomes (MLs) with active and magnetic targeting potential are evaluated as platform systems for drug targeting applications. USPIO‐encapsulating MLs are prepared by freeze drying/extrusion, decorated with one or two ligands for brain or… read more here.
Keywords: magnetic targeting; magnetoliposomes active; loaded magnetoliposomes; doxorubicin loaded ... See more keywords
Toxicological study of doxorubicin‐loaded PLGA nanoparticles for the treatment of glioblastoma
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Pharmaceutics"
DOI: 10.1016/j.ijpharm.2018.11.014
Abstract: Graphical abstract Figure. No caption available. Abstract Doxorubicin loaded in poloxamer 188‐coated PLGA nanoparticles (Dox‐NP + P188) was shown to produce a high antitumor effect against the experimental orthotopic 101.8 glioblastoma in rats upon intravenous… read more here.
Keywords: glioblastoma; plga nanoparticles; study; doxorubicin loaded ... See more keywords
Antitumor efficacy and cardiotoxic effect of doxorubicin-loaded mixed micelles in 4T1 murine breast cancer model. Comparative studies using Doxil® and free doxorubicin
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2020.101506
Abstract: Abstract Doxorubicin-loaded mixed micelles (DOX-micelles) were formulated employing TPGS and a poloxamine (Tetronic® T1107) in order to investigate their pharmaceutical application as an alternative anticancer nanotherapy. DOX-micelles presented unimodal behaviour, exhibiting average size values of… read more here.
Keywords: dox micelles; doxorubicin; loaded mixed; effect ... See more keywords
Doxorubicin-loaded biodegradable capsules: Temperature induced shrinking and study of cytotoxicity in vitro
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2019.03.152
Abstract: Abstract Doxorubicin (DOX) is one of mainstays in anticancer therapy due to its universal anticancer activity. Development of DOX delivery systems is of particular importance aiming a reduction in its non-targeted toxicity and improvement of… read more here.
Keywords: cytotoxicity; doxorubicin loaded; study; dox ... See more keywords
Ultrasound-Enhanced Delivery of Doxorubicin-Loaded Nanodiamonds from Pullulan-all-trans-Retinal Nanoparticles for Effective Cancer Therapy.
Sign Up to like & getrecommendations! Published in 2019 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.9b03559
Abstract: Nanodiamond as a drug carrier is of great significance in improving cancer therapy by overcoming chemoresistance. However, its clinical application is severely limited because of insufficient tumor vascular penetration. To address this limitation, pullulan-all-trans-retinal (pullulan-ATR)… read more here.
Keywords: pullulan trans; doxorubicin loaded; cancer; cancer therapy ... See more keywords
Drug-Loaded Biocompatible Chitosan Polymeric Films with Both Stretchability and Controlled Release for Drug Delivery
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c06719
Abstract: Chitosan is a natural polysaccharide with the advantageous qualities of biocompatibility and biodegradability, and it has recently been spotlighted as a soft material for a sustainable society. Advantages such as these are in demand for… read more here.
Keywords: biocompatible chitosan; doxorubicin loaded; acetic acid; loaded biocompatible ... See more keywords
Doxorubicin-loaded micelles with high drug-loading capacity and stability based on zwitterionic oligopeptides
Sign Up to like & getrecommendations! Published in 2020 at "New Journal of Chemistry"
DOI: 10.1039/d0nj02785e
Abstract: To simplify the preparation process and increase the drug-loading capacity of antitumor nanodrugs, doxorubicin-loaded micelles based on zwitterionic oligopeptides were fabricated through two step reactions in mild conditions. Zwitterionic oligopeptides Glu–Lys–Cys–Glu–Lys (EKCEK) were reacted with… read more here.
Keywords: drug loading; drug; loading capacity; doxorubicin loaded ... See more keywords
The Effect of Iodine-125 Radioactive Particle Stent with Doxorubicin-loaded Nano-tetrahedrons Combined with Transarterial Chemoembolization on Survival and Prognosis of Patients with Cholangiocarcinoma.
Sign Up to like & getrecommendations! Published in 2022 at "Cellular and molecular biology"
DOI: 10.14715/cmb/2022.68.8.24
Abstract: This study was to analyze the application of doxorubicin-loaded DNA nano-tetrahedral Iodine-125 (I-125) radioactive particle stent (doxorubicin-loaded 125I stent) combined with transarterial chemoembolization (TACE) in improving the prognosis of patients with cholangiocarcinoma (CC). The doxorubicin-loaded… read more here.
Keywords: prognosis; doxorubicin loaded; doxorubicin; group ... See more keywords
Doxorubicin-Loaded Poly (Lactic-Co-Glycolic Acid) Nanoparticles Coated with Chitosan/Alginate by Layer by Layer Technology for Antitumor Applications [Corrigendum]
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s322673
Abstract: [This corrects the article DOI: 10.2147/IJN.S130404.]. read more here.
Keywords: poly lactic; doxorubicin loaded; lactic glycolic; loaded poly ... See more keywords
Fabrication of Doxorubicin-Loaded Lipid-Based Nanocarriers by Microfluidic Rapid Mixing
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10061259
Abstract: Doxorubicin (Dox) is a widely known chemotherapeutic drug that has been encapsulated into liposomes for clinical use, such as Doxil® and Myocet®. Both of these are prepared via remote loading methods, which require multistep procedures.… read more here.
Keywords: doxorubicin loaded; doxorubicin; lipid based; lnc dox ... See more keywords