Study of the properties of doxorubicin-resistant cells affected by acute leucosis
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Bioenergetics and Biomembranes"
DOI: 10.1007/s10863-017-9738-4
Abstract: The stiffness of cell membrane was found to be one of the factors determining resistance of a cell in vitro to antibiotic doxorubicin action. Membranes of surviving cells are negatively charged (−35 – −30 mV) and… read more here.
Keywords: resistant cells; cells affected; affected acute; study properties ... See more keywords
Exostosin 1 regulates cancer cell stemness in doxorubicin-resistant breast cancer cells
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.19737
Abstract: Cancer stem cells (CSCs) are associated with cancer recurrence following radio/chemotherapy owing to their high resistance to therapeutic intervention. In this study, we investigated the role of exostoxin 1 (EXT1), an endoplasmic reticulum (ER)-residing type… read more here.
Keywords: cell stemness; cancer cell; cancer; cell ... See more keywords
The Molecular Mechanisms of Oleanane Aldehyde-β-enone Cytotoxicity against Doxorubicin-Resistant Cancer Cells
Sign Up to like & getrecommendations! Published in 2023 at "Biology"
DOI: 10.3390/biology12030415
Abstract: Simple Summary Currently, the main reason for the ineffectiveness of systemic chemotherapy is the formation of cancer cells with the phenotype of multiple drug resistance (MDR), which are able to survive at high doses of… read more here.
Keywords: cancer cells; dox; aldehyde enone; oleanane aldehyde ... See more keywords
Identification of Factors Driving Doxorubicin-Resistant Ewing Tumor Cells to Survival
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DOI: 10.3390/cancers14225498
Abstract: Simple Summary It is known that doxorubicin is one of the standards for chemotherapy treatment against Ewing sarcoma. Despite its widespread use, doxorubicin treatment initiates tumor escape mechanisms and disease relapse. Our study aims to… read more here.
Keywords: cell; ewing sarcoma; tumor cells; doxorubicin ... See more keywords
MDR1 Inhibition Reverses Doxorubicin-Resistance in Six Doxorubicin-Resistant Canine Prostate and Bladder Cancer Cell Lines
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DOI: 10.3390/ijms24098136
Abstract: Acquired chemoresistance during chemotherapy, often accompanied by cross- and multi-resistance, limits therapeutic outcomes and leads to recurrence. In order to create in vitro model systems to understand acquired doxorubicin-resistance, we generated doxorubicin-resistant sublines of canine… read more here.
Keywords: cell; doxorubicin resistance; resistance; cell lines ... See more keywords
Inhibitory Effect of Ursolic Acid on the Migration and Invasion of Doxorubicin-Resistant Breast Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27041282
Abstract: The cause of death in most breast cancer patients is disease metastasis and the occurrence of multidrug resistance (MDR). Ornithine decarboxylase (ODC), which is involved into multiple pathways, is closely related to carcinogenesis and development.… read more here.
Keywords: breast; ursolic acid; breast cancer; invasion ... See more keywords