Doxycycline attenuates l-DOPA-induced dyskinesia through an anti-inflammatory effect in a hemiparkinsonian mouse model
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DOI: 10.3389/fphar.2022.1045465
Abstract: The pharmacological manipulation of neuroinflammation appears to be a promising strategy to alleviate l-DOPA-induced dyskinesia (LID) in Parkinson’s disease (PD). Doxycycline (Doxy), a semisynthetic brain-penetrant tetracycline antibiotic having interesting anti-inflammatory properties, we addressed the possibility… read more here.
Keywords: induced dyskinesia; doxycycline attenuates; anti inflammatory; dopa induced ... See more keywords