A solid doxycycline HP-β-CD formulation for reconstitution (i.v. bolus) prepared by scaled-up electrospinning.
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DOI: 10.1016/j.ijpharm.2020.119539
Abstract: In this study a new intravenous (i.v.) bolus dosage form of doxycycline was prepared by electrospinning. A tetracycline-type antibiotic with low water solubility (doxycycline (DOX)) was used with 2-hydroxypropyl-β-cyclodextrin (HP-β-CD) as solubilizer. The new solid… read more here.
Keywords: formulation; formulation reconstitution; dox; doxycycline ... See more keywords