Dextran and peptide-based pH-sensitive hydrogel boosts healing process in multidrug-resistant bacteria-infected wounds.
Sign Up to like & getrecommendations! Published in 2022 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2021.118994
Abstract: Traumatic multidrug-resistant (MDR) bacterial infections are deadly threat to the public. To combat MDR bacteria, we developed a dual functional pH-sensitive hydrogel based on peptide DP7 (VQWRIRVAVIRK) and oxidized dextran (DP7-ODEX hydrogel). As an antimicrobial… read more here.
Keywords: healing process; sensitive hydrogel; dp7; multidrug resistant ... See more keywords
Antimicrobial peptide DP7 with potential activity against SARS coronavirus infections
Sign Up to like & getrecommendations! Published in 2021 at "Signal Transduction and Targeted Therapy"
DOI: 10.1038/s41392-021-00551-1
Abstract: Dear Editor, The outbreak of the SARS-CoV-2 epidemic once again demonstrates that RNA viruses, through mutations, genetic recombination and cross-species transmission, can pose a serious threat to the health of people worldwide. Even after the… read more here.
Keywords: dp7; cov protein; coronavirus; sars cov ... See more keywords
Antibacterial and antibiofilm activities of novel antimicrobial peptide DP7 against the periodontal pathogen Porphyromonas gingivalis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Microbiology"
DOI: 10.1111/jam.15614
Abstract: Accumulating evidence suggests that Porphyromonas gingivalis is closely associated with the development of various chronic inflammatory diseases, particularly periodontitis. This study investigated the antibacterial activity and action mechanism of a novel antimicrobial peptide (AMP), DP7,… read more here.
Keywords: novel antimicrobial; antimicrobial peptide; dp7; porphyromonas gingivalis ... See more keywords
Efficacy of Antimicrobial Peptide DP7, Designed by Machine-Learning Method, Against Methicillin-Resistant Staphylococcus aureus
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2019.01175
Abstract: Antimicrobial peptides (AMPs) provide a promising strategy against infections involving multidrug-resistant pathogens. In previous studies, we designed a short 12 amino acid AMP DP7, using a machine-learning method based on an amino acid activity contribution… read more here.
Keywords: dp7; machine learning; staphylococcus aureus; aureus ... See more keywords