Structure of human DPEP3 in complex with the SC-003 antibody Fab fragment reveals basis for lack of dipeptidase activity.
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DOI: 10.1016/j.jsb.2020.107512
Abstract: Dipeptidase 3 (DPEP3) is one of three glycosylphosphatidylinositol-anchored metallopeptidases potentially involved in the hydrolytic metabolism of dipeptides. While its exact biological function is not clear, DPEP3 expression is normally limited to testis , but can… read more here.
Keywords: fab fragment; dipeptidase; dpep3; antibody ... See more keywords