Sequential haematological and serum biochemical changes in Black Bengal goats infected with a local isolate of peste des petits ruminants virus from Bangladesh
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DOI: 10.1002/vms3.373
Abstract: Abstract Background Knowledge of sequential changes in haematobiochemical parameters of infected animals helps in the formulation of appropriate supportive therapy. Objective We investigated the sequential haematological and biochemical changes in peste des petits ruminants (PPR)‐infected… read more here.
Keywords: medicine; biochemical changes; sequential haematological; infected goats ... See more keywords
Hematological, biochemical, and histopathological responses in sorubim Pseudoplatystoma spp. experimentally infected with Lactococcus garvieae
Sign Up to like & getrecommendations! Published in 2020 at "Aquaculture International"
DOI: 10.1007/s10499-020-00566-5
Abstract: This study evaluated the hematological, biochemical, and histopathological responses of sorubim Pseudoplatystoma spp., experimentally infected with Lactococcus garvieae. Sorubim juveniles (n = 66; 21.3 ± 5.5 g; 17.1 ± 1.3 cm) were infected with L. garvieae by coelmatic inoculation (1.5 × 108 CFU… read more here.
Keywords: histopathological responses; hematological biochemical; garvieae; responses sorubim ... See more keywords
Efficient Nose-to-Lung Aerosol Delivery with an Inline DPI Requiring Low Actuation Air Volume
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DOI: 10.1007/s11095-018-2473-7
Abstract: PurposeTo demonstrate efficient aerosol delivery through an in vitro nasal model using a dry powder inhaler (DPI) requiring low actuation air volumes (LV) applied during low-flow nasal cannula (LFNC) therapy.MethodsA previously developed LV-DPI was connected… read more here.
Keywords: aerosol delivery; system; delivery; dpi requiring ... See more keywords
A Randomized, Double-Blind, Double-Dummy Study of Glycopyrrolate/Formoterol Fumarate Metered Dose Inhaler Relative to Umeclidinium/Vilanterol Dry Powder Inhaler in COPD
Sign Up to like & getrecommendations! Published in 2019 at "Advances in Therapy"
DOI: 10.1007/s12325-019-01015-3
Abstract: IntroductionGlycopyrrolate/formoterol fumarate metered dose inhaler (GFF MDI), formulated using co-suspension delivery technology, is the only approved fixed-dose combination long-acting muscarinic antagonist/long-acting β2-agonist (LAMA/LABA) delivered via MDI. Direct comparisons of GFF MDI versus other LAMA/LABAs have… read more here.
Keywords: gff mdi; inhaler; dpi; formoterol fumarate ... See more keywords
The dynamics of select cellular responses and cytokine expression profiles in mice infected with juvenile Clonorchis sinensis.
Sign Up to like & getrecommendations! Published in 2021 at "Acta tropica"
DOI: 10.1016/j.actatropica.2021.105852
Abstract: Clonorchiasis is a zoonotic disease that can result in chronic infection in humans. The causative agent, Clonorchis sinensis (C. sinensis), is believed to primarily induce a Th2 immune response in infected mice. However, few studies… read more here.
Keywords: dpi dpi; clonorchis sinensis; expression; dpi ... See more keywords
Diphenyleneiodonium enhances oxidative stress and inhibits Japanese encephalitis virus induced autophagy and ER stress pathways.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.05.149
Abstract: Diphenyleneiodonium (DPI) and N-acetyl-l-cysteine (NAC), two widely used anti-oxidants, were employed to evaluate the role of oxidative stress in Japanese encephalitis virus (JEV) induced autophagy, stress responses and replication. DPI and NAC exerted opposite effects… read more here.
Keywords: jev; dpi; japanese encephalitis; stress ... See more keywords
The RESPIRE trials: Two phase III, randomized, multicentre, placebo-controlled trials of Ciprofloxacin Dry Powder for Inhalation (Ciprofloxacin DPI) in non-cystic fibrosis bronchiectasis.
Sign Up to like & getrecommendations! Published in 2017 at "Contemporary clinical trials"
DOI: 10.1016/j.cct.2017.05.007
Abstract: The primary goals of long-term disease management in non-cystic fibrosis bronchiectasis (NCFB) are to reduce the number of exacerbations, and improve quality of life. However, currently no therapies are licensed for this. Ciprofloxacin Dry Powder… read more here.
Keywords: respire trials; treatment; dpi; ciprofloxacin dpi ... See more keywords
Exploring the influence of drug content on DPI powder properties and potential prediction of pulmonary drug deposition.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2019.119000
Abstract: Based on dry powder inhaler (DPI) inhalation process, powder properties have a key influence on fluidization and deagglomeration behavior during aerosol generation. The aim of this study was to explore the influence of drug content… read more here.
Keywords: powder properties; drug; powder; drug content ... See more keywords
Ghrelin attenuates infectious bursal disease virus–induced early inflammatory response and bursal injury in chicken
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DOI: 10.1016/j.psj.2020.08.010
Abstract: Studies demonstrated that chicken ghrelin mRNA was expressed in immune organs of chicken. However, it was not known for its functions in chicken immune system. This study aimed to investigate the effects of ghrelin on… read more here.
Keywords: infectious bursal; bursal injury; bursal; dpi ... See more keywords
Research Note: Expression of T cell-related cytokines in chicken cecal and spleen tissues following Eimeria tenella infection in vivo
Sign Up to like & getrecommendations! Published in 2021 at "Poultry Science"
DOI: 10.1016/j.psj.2021.101161
Abstract: The T cell-mediated immune response plays an important role in coccidiosis. To reveal the host T cell immune response following Eimeria tenella (E. tenella) infection in chickens, we performed quantitative real-time PCR to analyze the… read more here.
Keywords: related cytokines; infection; expression; cell ... See more keywords
Urine and tissue bacterial loads correlate with voiding behaviors in a murine urinary tract infection model.
Sign Up to like & getrecommendations! Published in 2021 at "Urology"
DOI: 10.1016/j.urology.2021.05.009
Abstract: OBJECTIVES To describe associations between voiding behavior and bacterial loads in a murine model of urinary tract infection (UTI). METHODS Fourteen female C57BL/6J mice were transurethrally inoculated with 108 colony forming unit uropathogenic E. coli… read more here.
Keywords: urinary tract; bacterial loads; infection; tissue ... See more keywords