The positive inotropic agent DPI-201106 selectively reverses ABCB1-mediated multidrug resistance in cancer cell lines.
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DOI: 10.1016/j.canlet.2018.07.022
Abstract: The overexpression of ABCB1 in cancer cells is a major factor contributing to the development of multidrug resistance (MDR) and treatment failure in cancer patients. Therefore, re-sensitization of MDR cancer cells to anticancer drugs remains… read more here.
Keywords: dpi 201106; cancer cells; multidrug resistance; cancer ... See more keywords