Understanding the generation and maintenance of supersaturation during the dissolution of amorphous solid dispersions using modulated DSC and 1H NMR.
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DOI: 10.1016/j.ijpharm.2017.11.056
Abstract: In this study, the dissolution behaviour of dipyridamole (DPM) and cinnarizine (CNZ) spray-dried amorphous solid dispersions (ASDs) using polyvinyl pyrrolidone (PVP) and polyacrylic acid (PAA) as a carrier matrix were evaluated and compared. The drug… read more here.
Keywords: drug; dissolution; dpm cnz; supersaturation ... See more keywords