Emergence of promising novel DPP‐4 inhibitory heterocycles as anti‐diabetic agents: A review
Sign Up to like & getrecommendations! Published in 2018 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.201800127
Abstract: Diabetes has turned out to be an epidemic in the recent years all over the world, and today it has become a burden on the healthcare system. Over the years, with technological advancements, different classes… read more here.
Keywords: novel dpp; inhibitory heterocycles; anti diabetic; emergence promising ... See more keywords
Synergistic modification of collagen structure using ionic liquid and ultrasound to promote the production of DPP-IV inhibitory peptides.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.12536
Abstract: BACKGROUND Dual modification of collagen was performed using ionic liquid (IL) and ultrasound (US) to modulate the activity of collagen hydrolyzed peptides and reveal the production mechanism of cowhide-derived DPP-IV inhibitory peptides. RESULTS The results… read more here.
Keywords: modification; liquid ultrasound; collagen; ionic liquid ... See more keywords
DPP‐IV Inhibitory Peptides From Whey Proteins: Production, Functional Mechanisms, Bibliometric Insights, and Future Directions for Type 2 Diabetes Therapy
Sign Up to like & getrecommendations! Published in 2025 at "Peptide Science"
DOI: 10.1002/pep2.70000
Abstract: This study addressed the therapeutic potential of dipeptidyl peptidase IV (DPP‐IV) inhibitory peptides obtained by whey protein hydrolysis as natural adjuvants to synthetic drugs for managing type 2 diabetes (T2D), a condition marked by insulin… read more here.
Keywords: bioactive compounds; dpp; type diabetes; dpp inhibitory ... See more keywords
Identification of novel dipeptidyl peptidase IV (DPP-IV) inhibitory peptides in camel milk protein hydrolysates.
Sign Up to like & getrecommendations! Published in 2018 at "Food chemistry"
DOI: 10.1016/j.foodchem.2017.10.033
Abstract: Nine novel dipeptidyl peptidase IV (DPP-IV) inhibitory peptides (FLQY, FQLGASPY, ILDKEGIDY, ILELA, LLQLEAIR, LPVP, LQALHQGQIV, MPVQA and SPVVPF) were identified in camel milk proteins hydrolysed with trypsin. This was achieved using a sequential approach combining… read more here.
Keywords: milk; camel milk; inhibitory peptides; dpp inhibitory ... See more keywords
Dipeptidyl peptidase IV (DPP-IV) inhibitory properties of a camel whey protein enriched hydrolysate preparation.
Sign Up to like & getrecommendations! Published in 2019 at "Food chemistry"
DOI: 10.1016/j.foodchem.2018.11.142
Abstract: Camel milk proteins contain dipeptidyl peptidase IV (DPP-IV) inhibitory peptides. A camel whey protein concentrate (WPC, 44.7 ± 3.4% (w/w) protein) was prepared and subsequently hydrolysed with trypsin at different temperatures, enzyme to substrate (E:S) ratios and… read more here.
Keywords: protein; dpp; dipeptidyl peptidase; dpp inhibitory ... See more keywords
Exploration of Dipeptidyl Peptidase-IV (DPP-IV) Inhibitory Peptides from Silkworm Pupae (Bombyx mori) Proteins Based on In Silico and In Vitro Assessments.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.1c08225
Abstract: This study aimed at exploring dipeptidyl peptidase-IV (DPP-IV) inhibitory peptides from silkworm pupae proteins by in silico analysis and in vitro assessments. In silico analysis of 274 silkworm pupae proteomes indicated that DPP-IV inhibitory peptides… read more here.
Keywords: dpp inhibitory; peptides silkworm; silkworm pupae; inhibitory peptides ... See more keywords
Rapid Screening of Novel Dipeptidyl Peptidase-4 Inhibitory Peptides from Pea (Pisum sativum L.) Protein Using Peptidomics and Molecular Docking.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c03949
Abstract: Pea protein hydrolysates (PPHs) possess good hypoglycemic effects; however, their dipeptidyl peptidase-4 (DPP-4) inhibitory activity is poorly understood, and none of the DPP-4 inhibitory peptides have been identified from PPHs. This paper aims to rapidly… read more here.
Keywords: molecular docking; dipeptidyl peptidase; inhibitory; dpp inhibitory ... See more keywords
Assessment of the DPP-IV inhibitory activity of a novel octapeptide derived from rapeseed using Caco-2 cell monolayers and molecular docking analysis.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of food biochemistry"
DOI: 10.1111/jfbc.13406
Abstract: The Octapeptide ELHQEEPL, which was identified from the rapeseed protein napin showed prominent Dipeptidyl peptidase-IV (DPP-IV) inhibitory activity. The objective of this study was to investigate the DPP-IV inhibitory activity and transepithelial transport of ELHQEEPL… read more here.
Keywords: cell monolayers; caco cell; activity; dpp inhibitory ... See more keywords
Potential of Dry-Cured Ham Bones as a Sustainable Source to Obtain Antioxidant and DPP-IV Inhibitory Extracts
Sign Up to like & getrecommendations! Published in 2023 at "Antioxidants"
DOI: 10.3390/antiox12061151
Abstract: The utilization of animal bones as a protein source could be used as a sustainable pathway for the production of bioactive compounds. In this study, bones were pretreated with pepsin enzyme (PEP) and then sequentially… read more here.
Keywords: hydrolysate; inhibitory; source; potential dry ... See more keywords
Identification, Screening, and Comprehensive Evaluation of Novel DPP-IV Inhibitory Peptides from the Tilapia Skin Gelatin Hydrolysate Produced Using Ginger Protease
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12121866
Abstract: Purpose: Inhibition of dipeptidyl peptidase-IV (DPP-IV) is an effective therapy for treating type II diabetes (T2D) that has been widely applied in clinical practice. We aimed to evaluate the DPP-IV inhibitory properties of ginger protease… read more here.
Keywords: dpp; skin gelatin; inhibitory; dpp inhibitory ... See more keywords
Identification and Characterization of Dipeptidyl Peptidase-IV Inhibitory Peptides from Oat Proteins
Sign Up to like & getrecommendations! Published in 2022 at "Foods"
DOI: 10.3390/foods11101406
Abstract: In this study, flavourzyme, papain, neutrase, and alcalase, as well as gastrointestinal digestion simulated with pepsin and pancreatin, were used to hydrolyze oat protein, and the dipeptidyl peptidase-IV (DPP-IV) inhibitory activities of the oat protein… read more here.
Keywords: dipeptidyl peptidase; oat protein; inhibitory; dpp inhibitory ... See more keywords